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Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Taha-Mehlitz S, Bianco G, Coto-Llerena M, Kancherla V, Bantug GR, Gallon J, Ercan C, Panebianco F, Eppenberger-Castori S, von Strauss M, Staubli S, Bolli M, Peterli R, Matter MS, Terracciano LM, von Flüe M, Ng CKY, Soysal SD, Kollmar O, Piscuoglio S. Taha-Mehlitz S, et al. Among authors: soysal sd. Theranostics. 2021 Feb 15;11(9):4011-4029. doi: 10.7150/thno.50051. eCollection 2021. Theranostics. 2021. PMID: 33754045 Free PMC article.
High frequency of CD8 positive lymphocyte infiltration correlates with lack of lymph node involvement in early rectal cancer.
Däster S, Eppenberger-Castori S, Hirt C, Zlobec I, Delko T, Nebiker CA, Soysal SD, Amicarella F, Iezzi G, Sconocchia G, Heberer M, Lugli A, Spagnoli GC, Kettelhack C, Terracciano L, Oertli D, von Holzen U, Tornillo L, Droeser RA. Däster S, et al. Among authors: soysal sd. Dis Markers. 2014;2014:792183. doi: 10.1155/2014/792183. Epub 2014 Dec 30. Dis Markers. 2014. PMID: 25609852 Free PMC article.
OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer.
Weixler B, Cremonesi E, Sorge R, Muraro MG, Delko T, Nebiker CA, Däster S, Governa V, Amicarella F, Soysal SD, Kettelhack C, von Holzen UW, Eppenberger-Castori S, Spagnoli GC, Oertli D, Iezzi G, Terracciano L, Tornillo L, Sconocchia G, Droeser RA. Weixler B, et al. Among authors: soysal sd. Oncotarget. 2015 Nov 10;6(35):37588-99. doi: 10.18632/oncotarget.5940. Oncotarget. 2015. PMID: 26439988 Free PMC article.
Absence of myeloperoxidase and CD8 positive cells in colorectal cancer infiltrates identifies patients with severe prognosis.
Däster S, Eppenberger-Castori S, Hirt C, Soysal SD, Delko T, Nebiker CA, Weixler B, Amicarella F, Iezzi G, Governa V, Padovan E, Mele V, Sconocchia G, Heberer M, Terracciano L, Kettelhack C, Oertli D, Spagnoli GC, von Holzen U, Tornillo L, Droeser RA. Däster S, et al. Among authors: soysal sd. Oncoimmunology. 2015 May 29;4(12):e1050574. doi: 10.1080/2162402X.2015.1050574. eCollection 2015 Dec. Oncoimmunology. 2015. PMID: 26587320 Free PMC article.
Phosphorylated CXCR4 expression has a positive prognostic impact in colorectal cancer.
Weixler B, Renetseder F, Facile I, Tosti N, Cremonesi E, Tampakis A, Delko T, Eppenberger-Castori S, Tzankov A, Iezzi G, Kettelhack C, Soysal SD, von Holzen U, Spagnoli GC, Terracciano L, Tornillo L, Droeser RA, Däster S. Weixler B, et al. Among authors: soysal sd. Cell Oncol (Dordr). 2017 Dec;40(6):609-619. doi: 10.1007/s13402-017-0348-2. Epub 2017 Sep 21. Cell Oncol (Dordr). 2017. PMID: 28936810
88 results