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The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models.
Brinch SA, Amundsen-Isaksen E, Espada S, Hammarström C, Aizenshtadt A, Olsen PA, Holmen L, Høyem M, Scholz H, Grødeland G, Sowa ST, Galera-Prat A, Lehtiö L, Meerts IATM, Leenders RGG, Wegert A, Krauss S, Waaler J. Brinch SA, et al. Among authors: sowa st. Cancer Res Commun. 2022 Apr 20;2(4):233-245. doi: 10.1158/2767-9764.CRC-22-0027. eCollection 2022 Apr. Cancer Res Commun. 2022. PMID: 36873622 Free PMC article.
Elucidation of the biosynthesis of the methane catalyst coenzyme F430.
Moore SJ, Sowa ST, Schuchardt C, Deery E, Lawrence AD, Ramos JV, Billig S, Birkemeyer C, Chivers PT, Howard MJ, Rigby SE, Layer G, Warren MJ. Moore SJ, et al. Among authors: sowa st. Nature. 2017 Mar 2;543(7643):78-82. doi: 10.1038/nature21427. Epub 2017 Feb 22. Nature. 2017. PMID: 28225763 Free PMC article.
Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor.
Waaler J, Leenders RGG, Sowa ST, Alam Brinch S, Lycke M, Nieczypor P, Aertssen S, Murthy S, Galera-Prat A, Damen E, Wegert A, Nazaré M, Lehtiö L, Krauss S. Waaler J, et al. Among authors: sowa st. J Med Chem. 2020 Jul 9;63(13):6834-6846. doi: 10.1021/acs.jmedchem.0c00208. Epub 2020 Jun 23. J Med Chem. 2020. PMID: 32511917 Free PMC article.
A molecular toolbox for ADP-ribosyl binding proteins.
Sowa ST, Galera-Prat A, Wazir S, Alanen HI, Maksimainen MM, Lehtiö L. Sowa ST, et al. Cell Rep Methods. 2021 Dec 20;1(8):100121. doi: 10.1016/j.crmeth.2021.100121. Epub 2021 Nov 11. Cell Rep Methods. 2021. PMID: 34786571 Free PMC article.
20 results