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Page 1
Multiepitope Proteins for the Differential Detection of IgG Antibodies against RBD of the Spike Protein and Non-RBD Regions of SARS-CoV-2.
Gomes LR, Durans AM, Napoleão-Pêgo P, Waterman JA, Freitas MS, De Sá NBR, Pereira LV, Furtado JS, Aquino RG, Machado MCR, Fintelman-Rodrigues N, Souza TML, Morel CM, Provance DW, De-Simone SG. Gomes LR, et al. Among authors: souza tml. Vaccines (Basel). 2021 Sep 3;9(9):986. doi: 10.3390/vaccines9090986. Vaccines (Basel). 2021. PMID: 34579223 Free PMC article.
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators.
Dias SSG, Soares VC, Ferreira AC, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, Teixeira L, Nunes da Silva MA, Barreto E, Mattos M, de Freitas CS, Azevedo-Quintanilha IG, Manso PPA, Miranda MD, Siqueira MM, Hottz ED, Pão CRR, Bou-Habib DC, Barreto-Vieira DF, Bozza FA, Souza TML, Bozza PT. Dias SSG, et al. Among authors: souza tml. PLoS Pathog. 2020 Dec 16;16(12):e1009127. doi: 10.1371/journal.ppat.1009127. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33326472 Free PMC article.
SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites.
Lechuga GC, Souza-Silva F, Sacramento CQ, Trugilho MRO, Valente RH, Napoleão-Pêgo P, Dias SSG, Fintelman-Rodrigues N, Temerozo JR, Carels N, Alves CR, Pereira MCS, Provance DW Jr, Souza TML, De-Simone SG. Lechuga GC, et al. Among authors: souza silva f, souza tml. Int J Mol Sci. 2021 Aug 21;22(16):9035. doi: 10.3390/ijms22169035. Int J Mol Sci. 2021. PMID: 34445741 Free PMC article.
WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2.
Aragão LGHS, Oliveira JT, Temerozo JR, Mendes MA, Salerno JA, Pedrosa CSG, Puig-Pijuan T, Veríssimo CP, Ornelas IM, Torquato T, Vitória G, Sacramento CQ, Fintelman-Rodrigues N, da Silva Gomes Dias S, Cardoso Soares V, Souza LRQ, Karmirian K, Goto-Silva L, Biagi D, Cruvinel EM, Dariolli R, Furtado DR, Bozza PT, Borges HL, Souza TML, Guimarães MZP, Rehen SK. Aragão LGHS, et al. Among authors: souza lrq, souza tml. PeerJ. 2021 Oct 8;9:e12262. doi: 10.7717/peerj.12262. eCollection 2021. PeerJ. 2021. PMID: 34707939 Free PMC article.
Polyclonal F(ab')2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency.
Cunha LER, Stolet AA, Strauch MA, Pereira VAR, Dumard CH, Gomes AMO, Monteiro FL, Higa LM, Souza PNC, Fonseca JG, Pontes FE, Meirelles LGR, Albuquerque JWM, Sacramento CQ, Fintelman-Rodrigues N, Lima TM, Alvim RGF, Marsili FF, Caldeira MM, Zingali RB, de Oliveira GAP, Souza TML, Silva AS, Muller R, Rodrigues DDRF, Jesus da Costa L, Alves ADR, Pinto MA, Oliveira AC, Guedes HLM, Tanuri A, Castilho LR, Silva JL. Cunha LER, et al. Among authors: souza pnc, souza tml. iScience. 2021 Nov 19;24(11):103315. doi: 10.1016/j.isci.2021.103315. Epub 2021 Oct 23. iScience. 2021. PMID: 34723156 Free PMC article.
Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating.
Salerno JA, Torquato T, Temerozo JR, Goto-Silva L, Karmirian K, Mendes MA, Sacramento CQ, Fintelman-Rodrigues N, Souza LRQ, Ornelas IM, Veríssimo CP, Aragão LGHS, Vitória G, Pedrosa CSG, da Silva Gomes Dias S, Cardoso Soares V, Puig-Pijuan T, Salazar V, Dariolli R, Biagi D, Furtado DR, Barreto Chiarini L, Borges HL, Bozza PT, Zaluar P Guimarães M, Souza TML, Rehen SK. Salerno JA, et al. Among authors: souza lrq, souza tml. PeerJ. 2021 Dec 20;9:e12595. doi: 10.7717/peerj.12595. eCollection 2021. PeerJ. 2021. PMID: 35036128 Free PMC article.
Severe influenza infection is associated with inflammatory programmed cell death in infected macrophages.
Ferreira AC, Sacramento CQ, Pereira-Dutra FS, Fintelman-Rodrigues N, Silva PP, Mattos M, de Freitas CS, Marttorelli A, de Melo GR, Campos MM, Azevedo-Quintanilha IG, Carlos AS, Emídio JV, Garcia CC, Bozza PT, Bozza FA, Souza TML. Ferreira AC, et al. Among authors: souza tml. Front Cell Infect Microbiol. 2023 Feb 16;13:1067285. doi: 10.3389/fcimb.2023.1067285. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36875528 Free PMC article.
Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation.
Soares VC, Dias SSG, Santos JC, Azevedo-Quintanilha IG, Moreira IBG, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, da Silva MAN, Barreto-Vieira DF, Souza TM, Bozza PT. Soares VC, et al. Life Sci Alliance. 2023 Sep 5;6(11):e202302049. doi: 10.26508/lsa.202302049. Print 2023 Nov. Life Sci Alliance. 2023. PMID: 37669865 Free PMC article.
Unveiling the Antiviral Capabilities of Targeting Human Dihydroorotate Dehydrogenase against SARS-CoV-2.
Purificação AD, Silva-Mendonça S, Cruz LV, Sacramento CQ, Temerozo JR, Fintelman-Rodrigues N, de Freitas CS, Godoi BF, Vaidergorn MM, Leite JA, Salazar Alvarez LC, Freitas MV, Silvac MFB, Martin BA, Lopez RFV, Neves BJ, Costa FTM, Souza TML, da Silva Emery F, Andrade CH, Nonato MC. Purificação AD, et al. Among authors: souza tml. ACS Omega. 2024 Feb 28;9(10):11418-11430. doi: 10.1021/acsomega.3c07845. eCollection 2024 Mar 12. ACS Omega. 2024. PMID: 38496952 Free PMC article.
The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle.
Ricciardi S, Guarino AM, Giaquinto L, Polishchuk EV, Santoro M, Di Tullio G, Wilson C, Panariello F, Soares VC, Dias SSG, Santos JC, Souza TML, Fusco G, Viscardi M, Brandi S, Bozza PT, Polishchuk RS, Venditti R, De Matteis MA. Ricciardi S, et al. Among authors: souza tml. Nature. 2022 Jun;606(7915):761-768. doi: 10.1038/s41586-022-04835-6. Epub 2022 May 12. Nature. 2022. PMID: 35551511 Free PMC article.
105 results