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Beta-hydroxybutyrate dampens adipose progenitors' profibrotic activation through canonical Tgfβ signaling and non-canonical ZFP36-dependent mechanisms.
Lecoutre S, Merabtene F, El Hachem EJ, Gamblin C, Rouault C, Sokolovska N, Soula H, Lai WS, Blackshear PJ, Clément K, Dugail I. Lecoutre S, et al. Among authors: soula h. Mol Metab. 2022 Jul;61:101512. doi: 10.1016/j.molmet.2022.101512. Epub 2022 May 9. Mol Metab. 2022. PMID: 35550189 Free PMC article.
Intestinal alteration of α-gustducin and sweet taste signaling pathway in metabolic diseases is partly rescued after weight loss and diabetes remission.
Le Gléau L, Rouault C, Osinski C, Prifti E, Soula HA, Debédat J, Busieau P, Amouyal C, Clément K, Andreelli F, Ribeiro A, Serradas P. Le Gléau L, et al. Am J Physiol Endocrinol Metab. 2021 Sep 1;321(3):E417-E432. doi: 10.1152/ajpendo.00071.2021. Epub 2021 Aug 2. Am J Physiol Endocrinol Metab. 2021. PMID: 34338041 Free article.
AhR activation defends gut barrier integrity against damage occurring in obesity.
Postal BG, Ghezzal S, Aguanno D, André S, Garbin K, Genser L, Brot-Laroche E, Poitou C, Soula H, Leturque A, Clément K, Carrière V. Postal BG, et al. Among authors: soula h. Mol Metab. 2020 Sep;39:101007. doi: 10.1016/j.molmet.2020.101007. Epub 2020 Apr 28. Mol Metab. 2020. PMID: 32360426 Free PMC article.
Long-Term Weight Outcome After Bariatric Surgery in Patients with Melanocortin-4 Receptor Gene Variants: a Case-Control Study of 105 Patients.
Cooiman MI, Alsters SIM, Duquesnoy M, Hazebroek EJ, Meijers-Heijboer HJ, Chahal H, Le Beyec-Le Bihan J, Clément K, Soula H, Blakemore AI, Poitou C, van Haelst MM. Cooiman MI, et al. Among authors: soula h. Obes Surg. 2022 Mar;32(3):837-844. doi: 10.1007/s11695-021-05869-x. Epub 2022 Jan 4. Obes Surg. 2022. PMID: 34984630
Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes.
Genser L, Aguanno D, Soula HA, Dong L, Trystram L, Assmann K, Salem JE, Vaillant JC, Oppert JM, Laugerette F, Michalski MC, Wind P, Rousset M, Brot-Laroche E, Leturque A, Clément K, Thenet S, Poitou C. Genser L, et al. J Pathol. 2018 Oct;246(2):217-230. doi: 10.1002/path.5134. Epub 2018 Aug 28. J Pathol. 2018. PMID: 29984492
47 results