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Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa.
Soukarieh F, Liu R, Romero M, Roberston SN, Richardson W, Lucanto S, Oton EV, Qudus NR, Mashabi A, Grossman S, Ali S, Sou T, Kukavica-Ibrulj I, Levesque RC, Bergström CAS, Halliday N, Mistry SN, Emsley J, Heeb S, Williams P, Cámara M, Stocks MJ. Soukarieh F, et al. Among authors: sou t. Front Chem. 2020 May 4;8:204. doi: 10.3389/fchem.2020.00204. eCollection 2020. Front Chem. 2020. PMID: 32432073 Free PMC article.
Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa.
Soukarieh F, Mashabi A, Richardson W, Oton EV, Romero M, Roberston SN, Grossman S, Sou T, Liu R, Halliday N, Kukavica-Ibrulj I, Levesque RC, Bergstrom CAS, Kellam B, Emsley J, Heeb S, Williams P, Stocks MJ, Cámara M. Soukarieh F, et al. Among authors: sou t. ACS Infect Dis. 2021 Sep 10;7(9):2666-2685. doi: 10.1021/acsinfecdis.1c00175. Epub 2021 Aug 17. ACS Infect Dis. 2021. PMID: 34503335 Free article.
Model-Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin.
Sou T, Hansen J, Liepinsh E, Backlund M, Ercan O, Grinberga S, Cao S, Giachou P, Petersson A, Tomczak M, Urbas M, Zabicka D, Vingsbo Lundberg C, Hughes D, Hobbie SN, Friberg LE. Sou T, et al. Clin Pharmacol Ther. 2021 Apr;109(4):1063-1073. doi: 10.1002/cpt.2104. Epub 2020 Nov 28. Clin Pharmacol Ther. 2021. PMID: 33150591 Free PMC article.
Pulmonary and systemic pharmacokinetics of colistin methanesulfonate (CMS) and formed colistin following nebulisation of CMS among patients with ventilator-associated pneumonia.
Gkoufa A, Sou T, Karaiskos I, Routsi C, Lin YW, Psichogiou M, Zakynthinos S, Giamarellou H, Li J, Friberg LE. Gkoufa A, et al. Among authors: sou t. Int J Antimicrob Agents. 2022 Jun;59(6):106588. doi: 10.1016/j.ijantimicag.2022.106588. Epub 2022 Apr 9. Int J Antimicrob Agents. 2022. PMID: 35405269
23 results