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Structural Protein Effects Underpinning Cognitive Developmental Delay of the PURA p.Phe233del Mutation Modelled by Artificial Intelligence and the Hybrid Quantum Mechanics-Molecular Mechanics Framework.
Brain Sci. 2022 Jun 30;12(7):871. doi: 10.3390/brainsci12070871.
Brain Sci. 2022.
PMID: 35884678
Free PMC article.
Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer's Disease Mutations.
Soto-Ospina A, Araque Marín P, Bedoya GJ, Villegas Lanau A.
Soto-Ospina A, et al.
Biochem Res Int. 2021 Nov 29;2021:9542038. doi: 10.1155/2021/9542038. eCollection 2021.
Biochem Res Int. 2021.
PMID: 34881055
Free PMC article.
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Protein Predictive Modeling and Simulation of Mutations of Presenilin-1 Familial Alzheimer's Disease on the Orthosteric Site.
Soto-Ospina A, Araque Marín P, Bedoya G, Sepulveda-Falla D, Villegas Lanau A.
Soto-Ospina A, et al.
Front Mol Biosci. 2021 Jun 2;8:649990. doi: 10.3389/fmolb.2021.649990. eCollection 2021.
Front Mol Biosci. 2021.
PMID: 34150846
Free PMC article.
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Mutations in SORL1 and MTHFDL1 possibly contribute to the development of Alzheimer's disease in a multigenerational Colombian Family.
Tejada Moreno JA, Villegas Lanau A, Madrigal Zapata L, Baena Pineda AY, Velez Hernandez J, Campo Nieto O, Soto Ospina A, Araque Marín P, Rishishwar L, Norris ET, Chande AT, Jordan IK, Bedoya Berrio G.
Tejada Moreno JA, et al. Among authors: soto ospina a.
PLoS One. 2022 Jul 29;17(7):e0269955. doi: 10.1371/journal.pone.0269955. eCollection 2022.
PLoS One. 2022.
PMID: 35905044
Free PMC article.
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Diffusion Mechanism Modeling of Metformin in Human Organic Cationic Amino Acid Transporter one and Functional Impact of S189L, R206C, and G401S Mutation.
Cano L, Soto-Ospina A, Araque P, Caro-Gomez MA, Parra-Marin MV, Bedoya G, Duque C.
Cano L, et al. Among authors: soto ospina a.
Front Pharmacol. 2021 Feb 9;11:587590. doi: 10.3389/fphar.2020.587590. eCollection 2020.
Front Pharmacol. 2021.
PMID: 33658930
Free PMC article.
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Genetic variants, structural, and functional changes of Myelin Protein Zero and Mannose-Binding Lectin 2 protein involved in immune response and its allelic transmission in families of patients with leprosy in Colombia.
Cardona-Pemberthy V, Rendón M, Beltrán JC, Soto-Ospina A, Muñoz-Gomez A, Araque-Marín P, Corredor M, Bedoya G, Cardona-Castro N.
Cardona-Pemberthy V, et al. Among authors: soto ospina a.
Infect Genet Evol. 2018 Jul;61:215-223. doi: 10.1016/j.meegid.2018.04.002. Epub 2018 Apr 5.
Infect Genet Evol. 2018.
PMID: 29627640
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Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1I249/M280 Variant.
Cardona SM, Kim SV, Church KA, Torres VO, Cleary IA, Mendiola AS, Saville SP, Watowich SS, Parker-Thornburg J, Soto-Ospina A, Araque P, Ransohoff RM, Cardona AE.
Cardona SM, et al. Among authors: soto ospina a.
Front Cell Neurosci. 2018 Oct 17;12:365. doi: 10.3389/fncel.2018.00365. eCollection 2018.
Front Cell Neurosci. 2018.
PMID: 30386211
Free PMC article.
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