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SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress.
Tangos M, Budde H, Kolijn D, Sieme M, Zhazykbayeva S, Lódi M, Herwig M, Gömöri K, Hassoun R, Robinson EL, Meister TL, Jaquet K, Kovács Á, Mustroph J, Evert K, Babel N, Fagyas M, Lindner D, Püschel K, Westermann D, Mannherz HG, Paneni F, Pfaender S, Tóth A, Mügge A, Sossalla S, Hamdani N. Tangos M, et al. Among authors: sossalla s. Int J Cardiol. 2022 Sep 1;362:196-205. doi: 10.1016/j.ijcard.2022.05.055. Epub 2022 May 26. Int J Cardiol. 2022. PMID: 35643215 Free PMC article.
Cardiac fibroblasts support cardiac inflammation in heart failure.
Lindner D, Zietsch C, Tank J, Sossalla S, Fluschnik N, Hinrichs S, Maier L, Poller W, Blankenberg S, Schultheiss HP, Tschöpe C, Westermann D. Lindner D, et al. Among authors: sossalla s. Basic Res Cardiol. 2014;109(5):428. doi: 10.1007/s00395-014-0428-7. Epub 2014 Aug 3. Basic Res Cardiol. 2014. PMID: 25086637
Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy.
Borchert T, Hübscher D, Guessoum CI, Lam TD, Ghadri JR, Schellinger IN, Tiburcy M, Liaw NY, Li Y, Haas J, Sossalla S, Huber MA, Cyganek L, Jacobshagen C, Dressel R, Raaz U, Nikolaev VO, Guan K, Thiele H, Meder B, Wollnik B, Zimmermann WH, Lüscher TF, Hasenfuss G, Templin C, Streckfuss-Bömeke K. Borchert T, et al. Among authors: sossalla s. J Am Coll Cardiol. 2017 Aug 22;70(8):975-991. doi: 10.1016/j.jacc.2017.06.061. J Am Coll Cardiol. 2017. PMID: 28818208 Free article.
SR Ca2+-leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure.
Mustroph J, Wagemann O, Lebek S, Tarnowski D, Ackermann J, Drzymalski M, Pabel S, Schmid C, Wagner S, Sossalla S, Maier LS, Neef S. Mustroph J, et al. Among authors: sossalla s. J Mol Cell Cardiol. 2018 Mar;116:81-90. doi: 10.1016/j.yjmcc.2018.02.002. Epub 2018 Feb 3. J Mol Cell Cardiol. 2018. PMID: 29410242 Free article.
Differential multivariable risk prediction of appropriate shock versus competing mortality - A prospective cohort study to estimate benefits from ICD therapy.
Bergau L, Willems R, Sprenkeler DJ, Fischer TH, Flevari P, Hasenfuß G, Katsaras D, Kirova A, Lehnart SE, Lüthje L, Röver C, Seegers J, Sossalla S, Dunnink A, Sritharan R, Tuinenburg AE, Vandenberk B, Vos MA, Wijers SC, Friede T, Zabel M. Bergau L, et al. Among authors: sossalla s. Int J Cardiol. 2018 Dec 1;272:102-107. doi: 10.1016/j.ijcard.2018.06.103. Epub 2018 Jun 28. Int J Cardiol. 2018. PMID: 29983251 Free article.
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.
Mustroph J, Wagemann O, Lücht CM, Trum M, Hammer KP, Sag CM, Lebek S, Tarnowski D, Reinders J, Perbellini F, Terracciano C, Schmid C, Schopka S, Hilker M, Zausig Y, Pabel S, Sossalla ST, Schweda F, Maier LS, Wagner S. Mustroph J, et al. Among authors: sossalla st. ESC Heart Fail. 2018 Aug;5(4):642-648. doi: 10.1002/ehf2.12336. ESC Heart Fail. 2018. PMID: 30117720 Free PMC article.
Empagliflozin directly improves diastolic function in human heart failure.
Pabel S, Wagner S, Bollenberg H, Bengel P, Kovács Á, Schach C, Tirilomis P, Mustroph J, Renner A, Gummert J, Fischer T, Van Linthout S, Tschöpe C, Streckfuss-Bömeke K, Hasenfuss G, Maier LS, Hamdani N, Sossalla S. Pabel S, et al. Among authors: sossalla s. Eur J Heart Fail. 2018 Dec;20(12):1690-1700. doi: 10.1002/ejhf.1328. Epub 2018 Oct 17. Eur J Heart Fail. 2018. PMID: 30328645 Free article.
Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice.
Pabel S, Ahmad S, Tirilomis P, Stehle T, Mustroph J, Knierim M, Dybkova N, Bengel P, Holzamer A, Hilker M, Streckfuss-Bömeke K, Hasenfuss G, Maier LS, Sossalla S. Pabel S, et al. Among authors: sossalla s. Basic Res Cardiol. 2020 Feb 20;115(2):20. doi: 10.1007/s00395-020-0780-8. Basic Res Cardiol. 2020. PMID: 32078054 Free PMC article.
Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation.
Kolijn D, Pabel S, Tian Y, Lódi M, Herwig M, Carrizzo A, Zhazykbayeva S, Kovács Á, Fülöp GÁ, Falcão-Pires I, Reusch PH, Linthout SV, Papp Z, van Heerebeek L, Vecchione C, Maier LS, Ciccarelli M, Tschöpe C, Mügge A, Bagi Z, Sossalla S, Hamdani N. Kolijn D, et al. Among authors: sossalla s. Cardiovasc Res. 2021 Jan 21;117(2):495-507. doi: 10.1093/cvr/cvaa123. Cardiovasc Res. 2021. PMID: 32396609
191 results