Sosič I - Search Results

1

Selective DNA Gyrase Inhibitors: Multi-Target in Silico Profiling with 3D-Pharmacophores.

Tomašič T, Zubrienė A, Skok Ž, Martini R, Pajk S, Sosič I, Ilaš J, Matulis D, Bryant SD. Tomašič T, et al. Among authors: sosic i. Pharmaceuticals (Basel). 2021 Aug 10;14(8):789. doi: 10.3390/ph14080789. Pharmaceuticals (Basel). 2021. PMID: 34451886 Free PMC article.

2

Design, synthesis, and evaluation of new thiadiazole-based direct inhibitors of enoyl acyl carrier protein reductase (InhA) for the treatment of tuberculosis.

Šink R, Sosič I, Živec M, Fernandez-Menendez R, Turk S, Pajk S, Alvarez-Gomez D, Lopez-Roman EM, Gonzales-Cortez C, Rullas-Triconado J, Angulo-Barturen I, Barros D, Ballell-Pages L, Young RJ, Encinas L, Gobec S. Šink R, et al. Among authors: sosic i. J Med Chem. 2015 Jan 22;58(2):613-24. doi: 10.1021/jm501029r. Epub 2014 Dec 29. J Med Chem. 2015. PMID: 25517015

3

New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold.

Pajk S, Živec M, Šink R, Sosič I, Neu M, Chung CW, Martínez-Hoyos M, Pérez-Herrán E, Álvarez-Gómez D, Álvarez-Ruíz E, Mendoza-Losana A, Castro-Pichel J, Barros D, Ballell-Pages L, Young RJ, Convery MA, Encinas L, Gobec S. Pajk S, et al. Among authors: sosic i. Eur J Med Chem. 2016 Apr 13;112:252-257. doi: 10.1016/j.ejmech.2016.02.008. Epub 2016 Feb 8. Eur J Med Chem. 2016. PMID: 26900657

4

Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα.

Bergant K, Janežič M, Valjavec K, Sosič I, Pajk S, Štampar M, Žegura B, Gobec S, Filipič M, Perdih A. Bergant K, et al. Among authors: sosic i. Eur J Med Chem. 2019 Aug 1;175:330-348. doi: 10.1016/j.ejmech.2019.04.055. Epub 2019 Apr 25. Eur J Med Chem. 2019. PMID: 31096154

5

Tunable Heteroaromatic Nitriles for Selective Bioorthogonal Click Reaction with Cysteine.

Proj M, Strašek N, Pajk S, Knez D, Sosič I. Proj M, et al. Among authors: sosic i. Bioconjug Chem. 2023 Jul 19;34(7):1271-1281. doi: 10.1021/acs.bioconjchem.3c00163. Epub 2023 Jun 24. Bioconjug Chem. 2023. PMID: 37354098 Free PMC article.

6

MurD enzymes from different bacteria: evaluation of inhibitors.

Barreteau H, Sosič I, Turk S, Humljan J, Tomašić T, Zidar N, Hervé M, Boniface A, Peterlin-Mašič L, Kikelj D, Mengin-Lecreulx D, Gobec S, Blanot D. Barreteau H, et al. Among authors: sosic i. Biochem Pharmacol. 2012 Sep 1;84(5):625-32. doi: 10.1016/j.bcp.2012.06.006. Epub 2012 Jun 15. Biochem Pharmacol. 2012. PMID: 22705647

7

Discovery of novel small-molecule compounds with selective cytotoxicity for Burkitt's lymphoma cells using 3D ligand-based virtual screening.

Gobec M, Sosič I, Brus B, Obreza A, Gobec S, Mlinarič-Raščan I. Gobec M, et al. Among authors: sosic i. Molecules. 2014 Nov 19;19(11):19209-19. doi: 10.3390/molecules191119209. Molecules. 2014. PMID: 25415480 Free PMC article.

8

Discovery of Immunoproteasome Inhibitors Using Large-Scale Covalent Virtual Screening.

Scarpino A, Bajusz D, Proj M, Gobec M, Sosič I, Gobec S, Ferenczy GG, Keserű GM. Scarpino A, et al. Among authors: sosic i. Molecules. 2019 Jul 16;24(14):2590. doi: 10.3390/molecules24142590. Molecules. 2019. PMID: 31315311 Free PMC article.

9

Psoralen Derivatives as Inhibitors of Mycobacterium tuberculosis Proteasome.

Rožman K, Alexander EM, Ogorevc E, Bozovičar K, Sosič I, Aldrich CC, Gobec S. Rožman K, et al. Among authors: sosic i. Molecules. 2020 Mar 12;25(6):1305. doi: 10.3390/molecules25061305. Molecules. 2020. PMID: 32178473 Free PMC article.

10

Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors.

Schiffrer ES, Proj M, Gobec M, Rejc L, Šterman A, Mravljak J, Gobec S, Sosič I. Schiffrer ES, et al. Among authors: sosic i. Molecules. 2021 Jan 12;26(2):356. doi: 10.3390/molecules26020356. Molecules. 2021. PMID: 33445542 Free PMC article.

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