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Molecular mechanism of the E99K mutation in cardiac actin (ACTC Gene) that causes apical hypertrophy in man and mouse.
Song W, Dyer E, Stuckey DJ, Copeland O, Leung MC, Bayliss C, Messer A, Wilkinson R, Tremoleda JL, Schneider MD, Harding SE, Redwood CS, Clarke K, Nowak K, Monserrat L, Wells D, Marston SB. Song W, et al. J Biol Chem. 2011 Aug 5;286(31):27582-93. doi: 10.1074/jbc.M111.252320. Epub 2011 May 26. J Biol Chem. 2011. PMID: 21622575 Free PMC article.
Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.
Rowlands CT, Owen T, Lawal S, Cao S, Pandey SS, Yang HY, Song W, Wilkinson R, Alvarez-Laviada A, Gehmlich K, Marston SB, MacLeod KT. Rowlands CT, et al. Among authors: song w. Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1213-H1226. doi: 10.1152/ajpheart.00244.2017. Epub 2017 Sep 8. Am J Physiol Heart Circ Physiol. 2017. PMID: 28887330 Free PMC article.
MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo.
Fiedler LR, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush PA, Bellahcene M, Noseda M, Faust D, Jarvis A, Newton G, Paiva MA, Harada M, Stuckey DJ, Song W, Habib J, Narasimhan P, Aqil R, Sanmugalingam D, Yan R, Pavanello L, Sano M, Wang SC, Sampson RD, Kanayaganam S, Taffet GE, Michael LH, Entman ML, Tan TH, Harding SE, Low CMR, Tralau-Stewart C, Perrior T, Schneider MD. Fiedler LR, et al. Among authors: song w. Cell Stem Cell. 2019 Apr 4;24(4):579-591.e12. doi: 10.1016/j.stem.2019.01.013. Epub 2019 Mar 7. Cell Stem Cell. 2019. PMID: 30853557 Free PMC article.
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