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The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages.
Toboz P, Amiri M, Tabatabaei N, Dufour CR, Kim SH, Fillebeen C, Ayemoba CE, Khoutorsky A, Nairz M, Shao L, Pajcini KV, Kim KW, Giguère V, Oliveira RL, Constante M, Santos MM, Morales CR, Pantopoulos K, Sonenberg N, Pinho S, Tahmasebi S. Toboz P, et al. Among authors: sonenberg n. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2121251119. doi: 10.1073/pnas.2121251119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994670 Free PMC article.
The target of rapamycin (TOR) proteins.
Raught B, Gingras AC, Sonenberg N. Raught B, et al. Among authors: sonenberg n. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7037-44. doi: 10.1073/pnas.121145898. Proc Natl Acad Sci U S A. 2001. PMID: 11416184 Free PMC article. Review.
Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production.
Alain T, Lun X, Martineau Y, Sean P, Pulendran B, Petroulakis E, Zemp FJ, Lemay CG, Roy D, Bell JC, Thomas G, Kozma SC, Forsyth PA, Costa-Mattioli M, Sonenberg N. Alain T, et al. Among authors: sonenberg n. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1576-81. doi: 10.1073/pnas.0912344107. Epub 2010 Jan 4. Proc Natl Acad Sci U S A. 2010. PMID: 20080710 Free PMC article.
Autism-related deficits via dysregulated eIF4E-dependent translational control.
Gkogkas CG, Khoutorsky A, Ran I, Rampakakis E, Nevarko T, Weatherill DB, Vasuta C, Yee S, Truitt M, Dallaire P, Major F, Lasko P, Ruggero D, Nader K, Lacaille JC, Sonenberg N. Gkogkas CG, et al. Among authors: sonenberg n. Nature. 2013 Jan 17;493(7432):371-7. doi: 10.1038/nature11628. Epub 2012 Nov 21. Nature. 2013. PMID: 23172145 Free PMC article.
Control of synaptic plasticity and memory via suppression of poly(A)-binding protein.
Khoutorsky A, Yanagiya A, Gkogkas CG, Fabian MR, Prager-Khoutorsky M, Cao R, Gamache K, Bouthiette F, Parsyan A, Sorge RE, Mogil JS, Nader K, Lacaille JC, Sonenberg N. Khoutorsky A, et al. Among authors: sonenberg n. Neuron. 2013 Apr 24;78(2):298-311. doi: 10.1016/j.neuron.2013.02.025. Neuron. 2013. PMID: 23622065 Free article.
Multifaceted regulation of somatic cell reprogramming by mRNA translational control.
Tahmasebi S, Alain T, Rajasekhar VK, Zhang JP, Prager-Khoutorsky M, Khoutorsky A, Dogan Y, Gkogkas CG, Petroulakis E, Sylvestre A, Ghorbani M, Assadian S, Yamanaka Y, Vinagolu-Baur JR, Teodoro JG, Kim K, Yang XJ, Sonenberg N. Tahmasebi S, et al. Among authors: sonenberg n. Cell Stem Cell. 2014 May 1;14(5):606-16. doi: 10.1016/j.stem.2014.02.005. Epub 2014 Mar 13. Cell Stem Cell. 2014. PMID: 24630793 Free article.
679 results