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Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria.
Kacsir I, Sipos A, Kiss T, Major E, Bajusz N, Tóth E, Buglyó P, Somsák L, Kardos G, Bai P, Bokor É. Kacsir I, et al. Among authors: somsak l. Front Chem. 2023 Jan 30;11:1086267. doi: 10.3389/fchem.2023.1086267. eCollection 2023. Front Chem. 2023. PMID: 36793764 Free PMC article.
New inhibitors of glycogen phosphorylase as potential antidiabetic agents.
Somsák L, Czifrák K, Tóth M, Bokor E, Chrysina ED, Alexacou KM, Hayes JM, Tiraidis C, Lazoura E, Leonidas DD, Zographos SE, Oikonomakos NG. Somsák L, et al. Curr Med Chem. 2008;15(28):2933-83. doi: 10.2174/092986708786848659. Curr Med Chem. 2008. PMID: 19075645 Review.
Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition.
Goyard D, Kónya B, Chajistamatiou AS, Chrysina ED, Leroy J, Balzarin S, Tournier M, Tousch D, Petit P, Duret C, Maurel P, Somsák L, Docsa T, Gergely P, Praly JP, Azay-Milhau J, Vidal S. Goyard D, et al. Among authors: somsak l. Eur J Med Chem. 2016 Jan 27;108:444-454. doi: 10.1016/j.ejmech.2015.12.004. Epub 2015 Dec 10. Eur J Med Chem. 2016. PMID: 26708111
102 results