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Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.
Duan J, Matute JD, Unger LW, Hanley T, Schnell A, Lin X, Krupka N, Griebel P, Lambden C, Sit B, Grootjans J, Pyzik M, Sommer F, Kaiser S, Falk-Paulsen M, Grasberger H, Kao JY, Fuhrer T, Li H, Paik D, Lee Y, Refetoff S, Glickman JN, Paton AW, Bry L, Paton JC, Sauer U, Macpherson AJ, Rosenstiel P, Kuchroo VK, Waldor MK, Huh JR, Kaser A, Blumberg RS. Duan J, et al. Among authors: sommer f. Immunity. 2023 May 9;56(5):1115-1131.e9. doi: 10.1016/j.immuni.2023.02.018. Epub 2023 Mar 13. Immunity. 2023. PMID: 36917985 Free PMC article.
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.
Pan WH, Sommer F, Falk-Paulsen M, Ulas T, Best L, Fazio A, Kachroo P, Luzius A, Jentzsch M, Rehman A, Müller F, Lengauer T, Walter J, Künzel S, Baines JF, Schreiber S, Franke A, Schultze JL, Bäckhed F, Rosenstiel P. Pan WH, et al. Among authors: sommer f. Genome Med. 2018 Apr 13;10(1):27. doi: 10.1186/s13073-018-0534-5. Genome Med. 2018. PMID: 29653584 Free PMC article.
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.
Mayr L, Grabherr F, Schwärzler J, Reitmeier I, Sommer F, Gehmacher T, Niederreiter L, He GW, Ruder B, Kunz KTR, Tymoszuk P, Hilbe R, Haschka D, Feistritzer C, Gerner RR, Enrich B, Przysiecki N, Seifert M, Keller MA, Oberhuber G, Sprung S, Ran Q, Koch R, Effenberger M, Tancevski I, Zoller H, Moschen AR, Weiss G, Becker C, Rosenstiel P, Kaser A, Tilg H, Adolph TE. Mayr L, et al. Among authors: sommer f. Nat Commun. 2020 Apr 14;11(1):1775. doi: 10.1038/s41467-020-15646-6. Nat Commun. 2020. PMID: 32286299 Free PMC article.
NOD2 Influences Trajectories of Intestinal Microbiota Recovery After Antibiotic Perturbation.
Moltzau Anderson J, Lipinski S, Sommer F, Pan WH, Boulard O, Rehman A, Falk-Paulsen M, Stengel ST, Aden K, Häsler R, Bharti R, Künzel S, Baines JF, Chamaillard M, Rosenstiel P. Moltzau Anderson J, et al. Among authors: sommer f. Cell Mol Gastroenterol Hepatol. 2020;10(2):365-389. doi: 10.1016/j.jcmgh.2020.03.008. Epub 2020 Apr 11. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32289499 Free PMC article.
PUFA-Induced Metabolic Enteritis as a Fuel for Crohn's Disease.
Schwärzler J, Mayr L, Vich Vila A, Grabherr F, Niederreiter L, Philipp M, Grander C, Meyer M, Jukic A, Tröger S, Enrich B, Przysiecki N, Tschurtschenthaler M, Sommer F, Kronberger I, Koch J, Hilbe R, Hess MW, Oberhuber G, Sprung S, Ran Q, Koch R, Effenberger M, Kaneider NC, Wieser V, Keller MA, Weersma RK, Aden K, Rosenstiel P, Blumberg RS, Kaser A, Tilg H, Adolph TE. Schwärzler J, et al. Among authors: sommer f. Gastroenterology. 2022 May;162(6):1690-1704. doi: 10.1053/j.gastro.2022.01.004. Epub 2022 Jan 12. Gastroenterology. 2022. PMID: 35031299 Free article.
608 results