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Immune-based biomarker accurately predicts response to imiquimod immunotherapy in cervical high-grade squamous intraepithelial lesions.
Abdulrahman Z, Hendriks N, J Kruse A, Somarakis A, J M van de Sande A, J van Beekhuizen H, M J Piek J, de Miranda NFCC, Kooreman LFS, F M Slangen B, van der Burg SH, de Vos van Steenwijk PJ, van Esch EMG. Abdulrahman Z, et al. Among authors: somarakis a. J Immunother Cancer. 2022 Nov;10(11):e005288. doi: 10.1136/jitc-2022-005288. J Immunother Cancer. 2022. PMID: 36323430 Free PMC article.
Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients.
Kenkhuis B, Somarakis A, de Haan L, Dzyubachyk O, IJsselsteijn ME, de Miranda NFCC, Lelieveldt BPF, Dijkstra J, van Roon-Mom WMC, Höllt T, van der Weerd L. Kenkhuis B, et al. Among authors: somarakis a. Acta Neuropathol Commun. 2021 Feb 17;9(1):27. doi: 10.1186/s40478-021-01126-5. Acta Neuropathol Commun. 2021. PMID: 33597025 Free PMC article.
Tumor-specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival.
Abdulrahman Z, Santegoets SJ, Sturm G, Charoentong P, Ijsselsteijn ME, Somarakis A, Höllt T, Finotello F, Trajanoski Z, van Egmond SL, Mustafa DAM, Welters MJP, de Miranda NFCC, van der Burg SH. Abdulrahman Z, et al. Among authors: somarakis a. J Immunother Cancer. 2022 Feb;10(2):e004346. doi: 10.1136/jitc-2021-004346. J Immunother Cancer. 2022. PMID: 35217577 Free PMC article.
VISTA Expression on Cancer-Associated Endothelium Selectively Prevents T-cell Extravasation.
Luk SJ, Schoppmeyer R, Ijsselsteijn ME, Somarakis A, Acem I, Remst DFG, Cox DT, van Bergen CAM, Briaire-de Bruijn I, Grönloh MLB, van der Meer WJ, Hawinkels LJAC, Koning RI, Bos E, Bovée JVMG, de Miranda NFCC, Szuhai K, van Buul JD, Falkenburg JHF, Heemskerk MHM. Luk SJ, et al. Among authors: somarakis a. Cancer Immunol Res. 2023 Nov 1;11(11):1480-1492. doi: 10.1158/2326-6066.CIR-22-0759. Cancer Immunol Res. 2023. PMID: 37695550
Visual cohort comparison for spatial single-cell omics-data.
Somarakis A, Ijsselsteijn ME, Luk SJ, Kenkhuis B, de Miranda NFCC, Lelieveldt BPF, Hollt T. Somarakis A, et al. IEEE Trans Vis Comput Graph. 2021 Feb;27(2):733-743. doi: 10.1109/TVCG.2020.3030336. Epub 2021 Jan 28. IEEE Trans Vis Comput Graph. 2021. PMID: 33112747
Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer.
Plattner C, Lamberti G, Blattmann P, Kirchmair A, Rieder D, Loncova Z, Sturm G, Scheidl S, Ijsselsteijn M, Fotakis G, Noureen A, Lisandrelli R, Böck N, Nemati N, Krogsdam A, Daum S, Finotello F, Somarakis A, Schäfer A, Wilflingseder D, Gonzalez Acera M, Öfner D, Huber LA, Clevers H, Becker C, Farin HF, Greten FR, Aebersold R, de Miranda NFCC, Trajanoski Z. Plattner C, et al. Among authors: somarakis a. iScience. 2023 Nov 4;26(12):108399. doi: 10.1016/j.isci.2023.108399. eCollection 2023 Dec 15. iScience. 2023. PMID: 38047086 Free PMC article.
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