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Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation.
Domingues N, Gaifem J, Matthiesen R, Saraiva DP, Bento L, Marques ARA, Soares MIL, Sampaio J, Klose C, Surma MA, Almeida MS, Rodrigues G, Gonçalves PA, Ferreira J, E Melo RG, Pedro LM, Simons K, Pinho E Melo TMVD, Cabral MG, Jacinto A, Silvestre R, Vaz W, Vieira OV. Domingues N, et al. Among authors: soares mil. J Lipid Res. 2023 Sep;64(9):100419. doi: 10.1016/j.jlr.2023.100419. Epub 2023 Jul 21. J Lipid Res. 2023. PMID: 37482218 Free PMC article.
Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages.
Domingues N, Marques ARA, Calado RDA, Ferreira IS, Ramos C, Ramalho J, Soares MIL, Pereira T, Oliveira L, Vicente JR, Wong LH, Simões ICM, Pinho E Melo TMVD, Peden A, Almeida CG, Futter CE, Puertollano R, Vaz WLC, Vieira OV. Domingues N, et al. Among authors: soares mil. Traffic. 2023 Jul;24(7):284-307. doi: 10.1111/tra.12888. Epub 2023 May 2. Traffic. 2023. PMID: 37129279 Free article.
A selective p53 activator and anticancer agent to improve colorectal cancer therapy.
Ramos H, Soares MIL, Silva J, Raimundo L, Calheiros J, Gomes C, Reis F, Monteiro FA, Nunes C, Reis S, Bosco B, Piazza S, Domingues L, Chlapek P, Vlcek P, Fabian P, Rajado AT, Carvalho ATP, Veselska R, Inga A, Pinho E Melo TMVD, Saraiva L. Ramos H, et al. Among authors: soares mil. Cell Rep. 2021 Apr 13;35(2):108982. doi: 10.1016/j.celrep.2021.108982. Cell Rep. 2021. PMID: 33852837 Free article.
Spiro-Lactams as Novel Antimicrobial Agents.
Alves AJS, Alves NG, Caratão CC, Esteves MIM, Fontinha D, Bártolo I, Soares MIL, Lopes SMM, Prudêncio M, Taveira N, Pinho E Melo TMVD. Alves AJS, et al. Among authors: soares mil. Curr Top Med Chem. 2020;20(2):140-152. doi: 10.2174/1568026619666191105110049. Curr Top Med Chem. 2020. PMID: 31702503
Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages.
Domingues N, Estronca LMBB, Silva J, Encarnação MR, Mateus R, Silva D, Santarino IB, Saraiva M, Soares MIL, Pinho E Melo TMVD, Jacinto A, Vaz WLC, Vieira OV. Domingues N, et al. Among authors: soares mil. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Feb;1862(2):210-220. doi: 10.1016/j.bbalip.2016.10.009. Epub 2016 Oct 26. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27793708 Free article.
18 results