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Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages.
Drummer C 4th, Saaoud F, Jhala NC, Cueto R, Sun Y, Xu K, Shao Y, Lu Y, Shen H, Yang L, Zhou Y, Yu J, Wu S, Snyder NW, Hu W, Zhuo J', Zhong Y, Jiang X, Wang H, Yang X. Drummer C 4th, et al. Among authors: snyder nw. Front Immunol. 2023 Jan 26;14:1113883. doi: 10.3389/fimmu.2023.1113883. eCollection 2023. Front Immunol. 2023. PMID: 36776889 Free PMC article.
Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways.
Saaoud F, Liu L, Xu K, Cueto R, Shao Y, Lu Y, Sun Y, Snyder NW, Wu S, Yang L, Zhou Y, Williams DL, Li C, Martinez L, Vazquez-Padron RI, Zhao H, Jiang X, Wang H, Yang X. Saaoud F, et al. Among authors: snyder nw. JCI Insight. 2023 Jan 10;8(1):e158183. doi: 10.1172/jci.insight.158183. JCI Insight. 2023. PMID: 36394956 Free PMC article.
ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development.
Lu Y, Sun Y, Saaoud F, Shao Y, Xu K, Jiang X, Wu S, Yu J, Snyder NW, Yang L, Shi XM, Zhao H, Wang H, Yang X. Lu Y, et al. Among authors: snyder nw. Front Immunol. 2023 Sep 4;14:1268916. doi: 10.3389/fimmu.2023.1268916. eCollection 2023. Front Immunol. 2023. PMID: 37731512 Free PMC article.
Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Among authors: snyder nw. Mol Metab. 2024 Mar;81:101888. doi: 10.1016/j.molmet.2024.101888. Epub 2024 Feb 1. Mol Metab. 2024. PMID: 38307385 Free PMC article.
132 results