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Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways.
Saaoud F, Liu L, Xu K, Cueto R, Shao Y, Lu Y, Sun Y, Snyder NW, Wu S, Yang L, Zhou Y, Williams DL, Li C, Martinez L, Vazquez-Padron RI, Zhao H, Jiang X, Wang H, Yang X. Saaoud F, et al. Among authors: snyder nw. JCI Insight. 2023 Jan 10;8(1):e158183. doi: 10.1172/jci.insight.158183. JCI Insight. 2023. PMID: 36394956 Free PMC article.
Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages.
Drummer C 4th, Saaoud F, Jhala NC, Cueto R, Sun Y, Xu K, Shao Y, Lu Y, Shen H, Yang L, Zhou Y, Yu J, Wu S, Snyder NW, Hu W, Zhuo J', Zhong Y, Jiang X, Wang H, Yang X. Drummer C 4th, et al. Among authors: snyder nw. Front Immunol. 2023 Jan 26;14:1113883. doi: 10.3389/fimmu.2023.1113883. eCollection 2023. Front Immunol. 2023. PMID: 36776889 Free PMC article.
ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development.
Lu Y, Sun Y, Saaoud F, Shao Y, Xu K, Jiang X, Wu S, Yu J, Snyder NW, Yang L, Shi XM, Zhao H, Wang H, Yang X. Lu Y, et al. Among authors: snyder nw. Front Immunol. 2023 Sep 4;14:1268916. doi: 10.3389/fimmu.2023.1268916. eCollection 2023. Front Immunol. 2023. PMID: 37731512 Free PMC article.
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression.
Tangudu NK, Buj R, Wang H, Wang J, Cole AR, Uboveja A, Fang R, Amalric A, Sajjakulnukit P, Lyons MA, Cooper K, Hempel N, Snyder NW, Lyssiotis CA, Chandran UR, Aird KM. Tangudu NK, et al. Among authors: snyder nw. bioRxiv [Preprint]. 2023 Sep 23:2023.07.15.549149. doi: 10.1101/2023.07.15.549149. bioRxiv. 2023. PMID: 37503050 Free PMC article. Updated. Preprint.
132 results