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Croquemort elicits activation of the immune deficiency pathway in ticks.
O'Neal AJ, Singh N, Rolandelli A, Laukaitis HJ, Wang X, Shaw DK, Young BD, Narasimhan S, Dutta S, Snyder GA, Samaddar S, Marnin L, Butler LR, Mendes MT, Cabrera Paz FE, Valencia LM, Sundberg EJ, Fikrig E, Pal U, Weber DJ, Pedra JHF. O'Neal AJ, et al. Among authors: snyder ga. Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2208673120. doi: 10.1073/pnas.2208673120. Epub 2023 May 8. Proc Natl Acad Sci U S A. 2023. PMID: 37155900 Free PMC article.
Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry.
Snyder GA, Deredge D, Waldhuber A, Fresquez T, Wilkins DZ, Smith PT, Durr S, Cirl C, Jiang J, Jennings W, Luchetti T, Snyder N, Sundberg EJ, Wintrode P, Miethke T, Xiao TS. Snyder GA, et al. Among authors: snyder n. J Biol Chem. 2014 Jan 10;289(2):669-79. doi: 10.1074/jbc.M113.523407. Epub 2013 Nov 25. J Biol Chem. 2014. PMID: 24275656 Free PMC article.
The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection.
Chen G, Wang X, Severo MS, Sakhon OS, Sohail M, Brown LJ, Sircar M, Snyder GA, Sundberg EJ, Ulland TK, Olivier AK, Andersen JF, Zhou Y, Shi GP, Sutterwala FS, Kotsyfakis M, Pedra JH. Chen G, et al. Among authors: snyder ga. Infect Immun. 2014 Jun;82(6):2553-64. doi: 10.1128/IAI.01679-14. Epub 2014 Mar 31. Infect Immun. 2014. PMID: 24686067 Free PMC article.
The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.
Wang X, Shaw DK, Sakhon OS, Snyder GA, Sundberg EJ, Santambrogio L, Sutterwala FS, Dumler JS, Shirey KA, Perkins DJ, Richard K, Chagas AC, Calvo E, Kopecký J, Kotsyfakis M, Pedra JHF. Wang X, et al. Among authors: snyder ga. Infect Immun. 2016 May 24;84(6):1796-1805. doi: 10.1128/IAI.01526-15. Print 2016 Jun. Infect Immun. 2016. PMID: 27045038 Free PMC article.
Infection-derived lipids elicit an immune deficiency circuit in arthropods.
Shaw DK, Wang X, Brown LJ, Chávez AS, Reif KE, Smith AA, Scott AJ, McClure EE, Boradia VM, Hammond HL, Sundberg EJ, Snyder GA, Liu L, DePonte K, Villar M, Ueti MW, de la Fuente J, Ernst RK, Pal U, Fikrig E, Pedra JH. Shaw DK, et al. Among authors: snyder ga. Nat Commun. 2017 Feb 14;8:14401. doi: 10.1038/ncomms14401. Nat Commun. 2017. PMID: 28195158 Free PMC article.
41 results