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The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles.
Snow AD, Castillo GM, Nguyen BP, Choi PY, Cummings JA, Cam J, Hu Q, Lake T, Pan W, Kastin AJ, Kirschner DA, Wood SG, Rockenstein E, Masliah E, Lorimer S, Tanzi RE, Larsen L. Snow AD, et al. Sci Rep. 2019 Feb 6;9(1):561. doi: 10.1038/s41598-019-38645-0. Sci Rep. 2019. PMID: 30728442 Free PMC article.
Fiber diffraction as a screen for amyloid inhibitors.
Kirschner DA, Gross AA, Hidalgo MM, Inouye H, Gleason KA, Abdelsayed GA, Castillo GM, Snow AD, Pozo-Ramajo A, Petty SA, Decatur SM. Kirschner DA, et al. Among authors: snow ad. Curr Alzheimer Res. 2008 Jun;5(3):288-307. doi: 10.2174/156720508784533295. Curr Alzheimer Res. 2008. PMID: 18537544
45 results