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Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.
Skácel J, Djukic S, Baszczyňski O, Kalčic F, Bílek T, Chalupský K, Kozák J, Dvořáková A, Tloušt'ová E, Král'ová Z, Šmídková M, Voldřich J, Rumlová M, Pachl P, Brynda J, Vučková T, Fábry M, Snášel J, Pichová I, Řezáčová P, Mertlíková-Kaiserová H, Janeba Z. Skácel J, et al. Among authors: snasel j. J Med Chem. 2023 May 25;66(10):6652-6681. doi: 10.1021/acs.jmedchem.2c02097. Epub 2023 May 3. J Med Chem. 2023. PMID: 37134237 Free PMC article.
Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides.
Snášel J, Nauš P, Dostál J, Hnízda A, Fanfrlík J, Brynda J, Bourderioux A, Dušek M, Dvořáková H, Stolaříková J, Zábranská H, Pohl R, Konečný P, Džubák P, Votruba I, Hajdúch M, Rezáčová P, Veverka V, Hocek M, Pichová I. Snášel J, et al. J Med Chem. 2014 Oct 23;57(20):8268-79. doi: 10.1021/jm500497v. Epub 2014 Oct 8. J Med Chem. 2014. PMID: 25259627
5'-Phosphonate modified oligoadenylates as potent activators of human RNase L.
Lášek T, Petrová M, Košiová I, Šimák O, Buděšínský M, Kozák J, Snášel J, Vavřina Z, Birkuš G, Rosenberg I, Páv O. Lášek T, et al. Among authors: snasel j. Bioorg Med Chem. 2022 Feb 15;56:116632. doi: 10.1016/j.bmc.2022.116632. Epub 2022 Jan 19. Bioorg Med Chem. 2022. PMID: 35078032
Corrigendum to "5'-Phosphonate modified oligoadenylates as potent activators of human RNase L" [Bioorg. Med. Chem. 56 (2022) 116632].
Lášek T, Petrová M, Košiová I, Šimák O, Buděšínský M, Kozák J, Snášel J, Vavřina Z, Birkuš G, Rosenberg I, Páv O. Lášek T, et al. Among authors: snasel j. Bioorg Med Chem. 2022 Mar 15;58:116654. doi: 10.1016/j.bmc.2022.116654. Epub 2022 Feb 10. Bioorg Med Chem. 2022. PMID: 35153131 No abstract available.
26 results