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TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Wils H, Kleinberger G, Janssens J, Pereson S, Joris G, Cuijt I, Smits V, Ceuterick-de Groote C, Van Broeckhoven C, Kumar-Singh S. Wils H, et al. Among authors: smits v. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3858-63. doi: 10.1073/pnas.0912417107. Epub 2010 Feb 3. Proc Natl Acad Sci U S A. 2010. PMID: 20133711 Free PMC article.
The neuroinflammatory role of Schwann cells in disease.
Ydens E, Lornet G, Smits V, Goethals S, Timmerman V, Janssens S. Ydens E, et al. Among authors: smits v. Neurobiol Dis. 2013 Jul;55:95-103. doi: 10.1016/j.nbd.2013.03.005. Epub 2013 Mar 21. Neurobiol Dis. 2013. PMID: 23523637 Review.
Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors.
Goethals O, Clayton R, Van Ginderen M, Vereycken I, Wagemans E, Geluykens P, Dockx K, Strijbos R, Smits V, Vos A, Meersseman G, Jochmans D, Vermeire K, Schols D, Hallenberger S, Hertogs K. Goethals O, et al. Among authors: smits v. J Virol. 2008 Nov;82(21):10366-74. doi: 10.1128/JVI.00470-08. Epub 2008 Aug 20. J Virol. 2008. PMID: 18715920 Free PMC article.
Cross-resistance profile determination of two second-generation HIV-1 integrase inhibitors using a panel of recombinant viruses derived from raltegravir-treated clinical isolates.
Van Wesenbeeck L, Rondelez E, Feyaerts M, Verheyen A, Van der Borght K, Smits V, Cleybergh C, De Wolf H, Van Baelen K, Stuyver LJ. Van Wesenbeeck L, et al. Among authors: smits v. Antimicrob Agents Chemother. 2011 Jan;55(1):321-5. doi: 10.1128/AAC.01733-09. Epub 2010 Oct 18. Antimicrob Agents Chemother. 2011. PMID: 20956600 Free PMC article.
Primary mutations selected in vitro with raltegravir confer large fold changes in susceptibility to first-generation integrase inhibitors, but minor fold changes to inhibitors with second-generation resistance profiles.
Goethals O, Vos A, Van Ginderen M, Geluykens P, Smits V, Schols D, Hertogs K, Clayton R. Goethals O, et al. Among authors: smits v. Virology. 2010 Jul 5;402(2):338-46. doi: 10.1016/j.virol.2010.03.034. Epub 2010 Apr 24. Virology. 2010. PMID: 20421122 Free article.
Resistance to raltegravir highlights integrase mutations at codon 148 in conferring cross-resistance to a second-generation HIV-1 integrase inhibitor.
Goethals O, Van Ginderen M, Vos A, Cummings MD, Van Der Borght K, Van Wesenbeeck L, Feyaerts M, Verheyen A, Smits V, Van Loock M, Hertogs K, Schols D, Clayton RF. Goethals O, et al. Among authors: smits v. Antiviral Res. 2011 Aug;91(2):167-76. doi: 10.1016/j.antiviral.2011.05.011. Epub 2011 Jun 12. Antiviral Res. 2011. PMID: 21669228
ATXN3 controls DNA replication and transcription by regulating chromatin structure.
Hernández-Carralero E, Cabrera E, Rodríguez-Torres G, Hernández-Reyes Y, Singh AN, Santa-María C, Fernández-Justel JM, Janssens RC, Marteijn JA, Evert BO, Mailand N, Gómez M, Ramadan K, Smits VAJ, Freire R. Hernández-Carralero E, et al. Among authors: smits vaj. Nucleic Acids Res. 2023 Jun 23;51(11):5396-5413. doi: 10.1093/nar/gkad212. Nucleic Acids Res. 2023. PMID: 36971114 Free PMC article.
48 results