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A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo.
Kirkland D, Whitwell J, Smith R, Hashimoto K, Ji Z, Kenny J, Koyama N, Lovell DP, Martus HJ, Meurer K, Roberts D, Takeiri A, Uno Y, van der Leede BJ, White P, Zeller A. Kirkland D, et al. Among authors: smith r. Mutat Res Genet Toxicol Environ Mutagen. 2022 Jul-Aug;879-880:503503. doi: 10.1016/j.mrgentox.2022.503503. Epub 2022 May 28. Mutat Res Genet Toxicol Environ Mutagen. 2022. PMID: 35914859 Free article.
Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. III: sensitivity of human cell types to known genotoxic agents.
Fowler P, Smith R, Smith K, Young J, Jeffrey L, Carmichael P, Kirkland D, Pfuhler S. Fowler P, et al. Among authors: smith k, smith r. Mutat Res Genet Toxicol Environ Mutagen. 2014 Jun;767:28-36. doi: 10.1016/j.mrgentox.2014.03.001. Epub 2014 Mar 13. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 24632063
Relationships between p53 status, apoptosis and induction of micronuclei in different human and mouse cell lines in vitro: Implications for improving existing assays.
Whitwell J, Smith R, Jenner K, Lyon H, Wood D, Clements J, Aschcroft-Hawley K, Gollapudi B, Kirkland D, Lorge E, Pfuhler S, Tanir JY, Thybaud V. Whitwell J, et al. Among authors: smith r. Mutat Res Genet Toxicol Environ Mutagen. 2015 Aug;789-790:7-27. doi: 10.1016/j.mrgentox.2015.05.011. Epub 2015 May 30. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26232254
Analysis of negative historical control group data from the in vitro micronucleus assay using TK6 cells.
Lovell DP, Fellows M, Marchetti F, Christiansen J, Elhajouji A, Hashimoto K, Kasamoto S, Li Y, Masayasu O, Moore MM, Schuler M, Smith R, Stankowski LF Jr, Tanaka J, Tanir JY, Thybaud V, Van Goethem F, Whitwell J. Lovell DP, et al. Among authors: smith r. Mutat Res Genet Toxicol Environ Mutagen. 2018 Jan;825:40-50. doi: 10.1016/j.mrgentox.2017.10.006. Epub 2017 Nov 10. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 29307374 Free article.
Analysis of historical negative control group data from the rat in vivo micronucleus assay.
Lovell DP, Fellows M, Saul J, Whitwell J, Custer L, Dertinger S, Escobar P, Fiedler R, Hemmann U, Kenny J, Smith R, van der Leede BM, Zeller A. Lovell DP, et al. Among authors: smith r. Mutat Res Genet Toxicol Environ Mutagen. 2020 Jan;849:503086. doi: 10.1016/j.mrgentox.2019.503086. Epub 2019 Oct 12. Mutat Res Genet Toxicol Environ Mutagen. 2020. PMID: 32087845
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT).
Dertinger SD, Li D, Beevers C, Douglas GR, Heflich RH, Lovell DP, Roberts DJ, Smith R, Uno Y, Williams A, Witt KL, Zeller A, Zhou C. Dertinger SD, et al. Among authors: smith r. Environ Mol Mutagen. 2023 Apr 25:10.1002/em.22541. doi: 10.1002/em.22541. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 37097075 Review.
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