TIGIT blockade repolarizes AML-associated TIGIT+ M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck F, Fischer B, Witt M, Muschhammer J, Oelrich J, da Costa Avelar PH, Tsoka S, Bullinger L, Seubert E, Smit DJ, Bokemeyer C, Ackermann C, Wellbrock J, Haag F, Fiedler W.
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J Immunother Cancer. 2022 Dec;10(12):e004794. doi: 10.1136/jitc-2022-004794.
J Immunother Cancer. 2022.
PMID: 36549780
Free PMC article.