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New Promise and Opportunities for Allosteric Kinase Inhibitors.
Lu X, Smaill JB, Ding K. Lu X, et al. Among authors: smaill jb. Angew Chem Int Ed Engl. 2020 Aug 10;59(33):13764-13776. doi: 10.1002/anie.201914525. Epub 2020 Apr 1. Angew Chem Int Ed Engl. 2020. PMID: 31889388 Review.
Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia.
Guise CP, Mowday AM, Ashoorzadeh A, Yuan R, Lin WH, Wu DH, Smaill JB, Patterson AV, Ding K. Guise CP, et al. Among authors: smaill jb. Chin J Cancer. 2014 Feb;33(2):80-6. doi: 10.5732/cjc.012.10285. Epub 2013 Jul 12. Chin J Cancer. 2014. PMID: 23845143 Free PMC article. Review.
N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors.
Li Y, Cheng H, Zhang Z, Zhuang X, Luo J, Long H, Zhou Y, Xu Y, Taghipouran R, Li D, Patterson A, Smaill J, Tu Z, Wu D, Ren X, Ding K. Li Y, et al. ACS Med Chem Lett. 2015 Mar 18;6(5):543-7. doi: 10.1021/acsmedchemlett.5b00039. eCollection 2015 May 14. ACS Med Chem Lett. 2015. PMID: 26005530 Free PMC article.
2-Oxo-3, 4-dihydropyrimido[4, 5-d]pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors.
Li X, Guise CP, Taghipouran R, Yosaatmadja Y, Ashoorzadeh A, Paik WK, Squire CJ, Jiang S, Luo J, Xu Y, Tu ZC, Lu X, Ren X, Patterson AV, Smaill JB, Ding K. Li X, et al. Among authors: smaill jb. Eur J Med Chem. 2017 Jul 28;135:531-543. doi: 10.1016/j.ejmech.2017.04.049. Epub 2017 Apr 22. Eur J Med Chem. 2017. PMID: 28521156
Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer.
Xiang Q, Wang C, Zhang Y, Xue X, Song M, Zhang C, Li C, Wu C, Li K, Hui X, Zhou Y, Smaill JB, Patterson AV, Wu D, Ding K, Xu Y. Xiang Q, et al. Among authors: smaill jb. Eur J Med Chem. 2018 Mar 10;147:238-252. doi: 10.1016/j.ejmech.2018.01.087. Epub 2018 Feb 6. Eur J Med Chem. 2018. PMID: 29448139
75 results