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Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation.
Merlin J, Ivanov S, Dumont A, Sergushichev A, Gall J, Stunault M, Ayrault M, Vaillant N, Castiglione A, Swain A, Orange F, Gallerand A, Berton T, Martin JC, Carobbio S, Masson J, Gaisler-Salomon I, Maechler P, Rayport S, Sluimer JC, Biessen EAL, Guinamard RR, Gautier EL, Thorp EB, Artyomov MN, Yvan-Charvet L. Merlin J, et al. Among authors: sluimer jc. Nat Metab. 2021 Oct;3(10):1313-1326. doi: 10.1038/s42255-021-00471-y. Epub 2021 Oct 14. Nat Metab. 2021. PMID: 34650273 Free PMC article.
Macrophage autophagy plays a protective role in advanced atherosclerosis.
Liao X, Sluimer JC, Wang Y, Subramanian M, Brown K, Pattison JS, Robbins J, Martinez J, Tabas I. Liao X, et al. Among authors: sluimer jc. Cell Metab. 2012 Apr 4;15(4):545-53. doi: 10.1016/j.cmet.2012.01.022. Epub 2012 Mar 22. Cell Metab. 2012. PMID: 22445600 Free PMC article.
Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis.
Marsch E, Theelen TL, Demandt JA, Jeurissen M, van Gink M, Verjans R, Janssen A, Cleutjens JP, Meex SJ, Donners MM, Haenen GR, Schalkwijk CG, Dubois LJ, Lambin P, Mallat Z, Gijbels MJ, Heemskerk JW, Fisher EA, Biessen EA, Janssen BJ, Daemen MJ, Sluimer JC. Marsch E, et al. Among authors: sluimer jc. Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2545-53. doi: 10.1161/ATVBAHA.114.304023. Epub 2014 Sep 25. Arterioscler Thromb Vasc Biol. 2014. PMID: 25256233
Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice.
Theelen TL, Lappalainen JP, Sluimer JC, Gurzeler E, Cleutjens JP, Gijbels MJ, Biessen EA, Daemen MJ, Alitalo K, Ylä-Herttuala S. Theelen TL, et al. Among authors: sluimer jc. Atherosclerosis. 2015 Aug;241(2):297-304. doi: 10.1016/j.atherosclerosis.2015.05.018. Epub 2015 Jun 3. Atherosclerosis. 2015. PMID: 26062989 Free PMC article.
Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility.
Medina I, Cougoule C, Drechsler M, Bermudez B, Koenen RR, Sluimer J, Wolfs I, Döring Y, Herias V, Gijbels M, Bot I, de Jager S, Weber C, Cleutjens J, van Berkel TJC, Sikkink KJ, Mócsai A, Maridonneau-Parini I, Soehnlein O, Biessen EAL. Medina I, et al. Circulation. 2015 Aug 11;132(6):490-501. doi: 10.1161/CIRCULATIONAHA.114.012316. Epub 2015 Jun 11. Circulation. 2015. PMID: 26068045 Free PMC article.
Feasibility of in vivo 18F-florbetaben PET/MR imaging of human carotid amyloid-β.
Bucerius J, Barthel H, Tiepolt S, Werner P, Sluimer JC, Wildberger JE, Patt M, Hesse S, Gertz HJ, Biessen EAL, Mottaghy FM, Sabri O. Bucerius J, et al. Among authors: sluimer jc. Eur J Nucl Med Mol Imaging. 2017 Jul;44(7):1119-1128. doi: 10.1007/s00259-017-3651-2. Epub 2017 Mar 21. Eur J Nucl Med Mol Imaging. 2017. PMID: 28321471 Free PMC article.
Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells.
Fontaine MAC, Westra MM, Bot I, Jin H, Franssen AJPM, Bot M, de Jager SCA, Dzhagalov I, He YW, van Vlijmen BJM, Gijbels MJJ, Reutelingsperger CP, van Berkel TJC, Sluimer JC, Temmerman L, Biessen EAL. Fontaine MAC, et al. Among authors: sluimer jc. Sci Rep. 2019 Oct 10;9(1):14547. doi: 10.1038/s41598-019-51020-3. Sci Rep. 2019. PMID: 31601924 Free PMC article.
Novel Plaque Enriched Long Noncoding RNA in Atherosclerotic Macrophage Regulation (PELATON).
Hung J, Scanlon JP, Mahmoud AD, Rodor J, Ballantyne M, Fontaine MAC, Temmerman L, Kaczynski J, Connor KL, Bhushan R, Biessen EAL, Newby DE, Sluimer JC, Baker AH. Hung J, et al. Among authors: sluimer jc. Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):697-713. doi: 10.1161/ATVBAHA.119.313430. Epub 2019 Dec 12. Arterioscler Thromb Vasc Biol. 2020. PMID: 31826651 Free PMC article.
90 results