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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
Zetsche B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F. Zetsche B, et al. Among authors: slaymaker im. Cell. 2015 Oct 22;163(3):759-71. doi: 10.1016/j.cell.2015.09.038. Epub 2015 Sep 25. Cell. 2015. PMID: 26422227 Free PMC article.
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA.
Yamano T, Nishimasu H, Zetsche B, Hirano H, Slaymaker IM, Li Y, Fedorova I, Nakane T, Makarova KS, Koonin EV, Ishitani R, Zhang F, Nureki O. Yamano T, et al. Among authors: slaymaker im. Cell. 2016 May 5;165(4):949-62. doi: 10.1016/j.cell.2016.04.003. Epub 2016 Apr 21. Cell. 2016. PMID: 27114038 Free PMC article.
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.
Abudayyeh OO, Gootenberg JS, Konermann S, Joung J, Slaymaker IM, Cox DB, Shmakov S, Makarova KS, Semenova E, Minakhin L, Severinov K, Regev A, Lander ES, Koonin EV, Zhang F. Abudayyeh OO, et al. Among authors: slaymaker im. Science. 2016 Aug 5;353(6299):aaf5573. doi: 10.1126/science.aaf5573. Epub 2016 Jun 2. Science. 2016. PMID: 27256883 Free PMC article.
Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits.
Platt RJ, Zhou Y, Slaymaker IM, Shetty AS, Weisbach NR, Kim JA, Sharma J, Desai M, Sood S, Kempton HR, Crabtree GR, Feng G, Zhang F. Platt RJ, et al. Among authors: slaymaker im. Cell Rep. 2017 Apr 11;19(2):335-350. doi: 10.1016/j.celrep.2017.03.052. Cell Rep. 2017. PMID: 28402856 Free PMC article.
CRISPR-Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling.
Tangprasertchai NS, Di Felice R, Zhang X, Slaymaker IM, Vazquez Reyes C, Jiang W, Rohs R, Qin PZ. Tangprasertchai NS, et al. Among authors: slaymaker im. ACS Chem Biol. 2017 Jun 16;12(6):1489-1493. doi: 10.1021/acschembio.6b01137. Epub 2017 May 3. ACS Chem Biol. 2017. PMID: 28437608 Free PMC article.
Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation.
Chu SH, Packer M, Rees H, Lam D, Yu Y, Marshall J, Cheng LI, Lam D, Olins J, Ran FA, Liquori A, Gantzer B, Decker J, Born D, Barrera L, Hartigan A, Gaudelli N, Ciaramella G, Slaymaker IM. Chu SH, et al. Among authors: slaymaker im. CRISPR J. 2021 Apr;4(2):169-177. doi: 10.1089/crispr.2020.0144. CRISPR J. 2021. PMID: 33876959
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