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Prolonged force depression after mechanically demanding contractions is largely independent of Ca2+ and reactive oxygen species.
Kamandulis S, de Souza Leite F, Hernández A, Katz A, Brazaitis M, Bruton JD, Venckunas T, Masiulis N, Mickeviciene D, Eimantas N, Subocius A, Rassier DE, Skurvydas A, Ivarsson N, Westerblad H. Kamandulis S, et al. Among authors: skurvydas a. FASEB J. 2017 Nov;31(11):4809-4820. doi: 10.1096/fj.201700019R. Epub 2017 Jul 17. FASEB J. 2017. PMID: 28716970
In conclusion, PLFFD caused by mechanically demanding eccentric contractions does not involve any major increase in ROS or RyR1 fragmentation.-Kamandulis, S., de Souza Leite, F., Hernandez, A., Katz, A., Brazaitis, M., Bruton, J. D., Venckunas, T., Masiulis, N., Mic …
In conclusion, PLFFD caused by mechanically demanding eccentric contractions does not involve any major increase in ROS or RyR1 fragmentatio …
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