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H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction.
Healton SE, Pinto HD, Mishra LN, Hamilton GA, Wheat JC, Swist-Rosowska K, Shukeir N, Dou Y, Steidl U, Jenuwein T, Gamble MJ, Skoultchi AI. Healton SE, et al. Among authors: skoultchi ai. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14251-14258. doi: 10.1073/pnas.1920725117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513732 Free PMC article.
H1 histones control the epigenetic landscape by local chromatin compaction.
Willcockson MA, Healton SE, Weiss CN, Bartholdy BA, Botbol Y, Mishra LN, Sidhwani DS, Wilson TJ, Pinto HB, Maron MI, Skalina KA, Toro LN, Zhao J, Lee CH, Hou H, Yusufova N, Meydan C, Osunsade A, David Y, Cesarman E, Melnick AM, Sidoli S, Garcia BA, Edelmann W, Macian F, Skoultchi AI. Willcockson MA, et al. Among authors: skoultchi ai. Nature. 2021 Jan;589(7841):293-298. doi: 10.1038/s41586-020-3032-z. Epub 2020 Dec 9. Nature. 2021. PMID: 33299182 Free PMC article.
Local compartment changes and regulatory landscape alterations in histone H1-depleted cells.
Geeven G, Zhu Y, Kim BJ, Bartholdy BA, Yang SM, Macfarlan TS, Gifford WD, Pfaff SL, Verstegen MJ, Pinto H, Vermunt MW, Creyghton MP, Wijchers PJ, Stamatoyannopoulos JA, Skoultchi AI, de Laat W. Geeven G, et al. Among authors: skoultchi ai. Genome Biol. 2015 Dec 23;16:289. doi: 10.1186/s13059-015-0857-0. Genome Biol. 2015. PMID: 26700097 Free PMC article.
Mice develop normally without the H1(0) linker histone.
Sirotkin AM, Edelmann W, Cheng G, Klein-Szanto A, Kucherlapati R, Skoultchi AI. Sirotkin AM, et al. Among authors: skoultchi ai. Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6434-8. doi: 10.1073/pnas.92.14.6434. Proc Natl Acad Sci U S A. 1995. PMID: 7604008 Free PMC article.
Single-molecule imaging of transcription dynamics in somatic stem cells.
Wheat JC, Sella Y, Willcockson M, Skoultchi AI, Bergman A, Singer RH, Steidl U. Wheat JC, et al. Among authors: skoultchi ai. Nature. 2020 Jul;583(7816):431-436. doi: 10.1038/s41586-020-2432-4. Epub 2020 Jun 24. Nature. 2020. PMID: 32581360 Free PMC article.
Mammalian linker-histone subtypes differentially affect gene expression in vivo.
Alami R, Fan Y, Pack S, Sonbuchner TM, Besse A, Lin Q, Greally JM, Skoultchi AI, Bouhassira EE. Alami R, et al. Among authors: skoultchi ai. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5920-5. doi: 10.1073/pnas.0736105100. Epub 2003 Apr 28. Proc Natl Acad Sci U S A. 2003. PMID: 12719535 Free PMC article.
143 results