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Page 1
Greenlandic Inuit show genetic signatures of diet and climate adaptation.
Fumagalli M, Moltke I, Grarup N, Racimo F, Bjerregaard P, Jørgensen ME, Korneliussen TS, Gerbault P, Skotte L, Linneberg A, Christensen C, Brandslund I, Jørgensen T, Huerta-Sánchez E, Schmidt EB, Pedersen O, Hansen T, Albrechtsen A, Nielsen R. Fumagalli M, et al. Among authors: skotte l. Science. 2015 Sep 18;349(6254):1343-7. doi: 10.1126/science.aab2319. Science. 2015. PMID: 26383953 Free article.
An Aboriginal Australian genome reveals separate human dispersals into Asia.
Rasmussen M, Guo X, Wang Y, Lohmueller KE, Rasmussen S, Albrechtsen A, Skotte L, Lindgreen S, Metspalu M, Jombart T, Kivisild T, Zhai W, Eriksson A, Manica A, Orlando L, De La Vega FM, Tridico S, Metspalu E, Nielsen K, Ávila-Arcos MC, Moreno-Mayar JV, Muller C, Dortch J, Gilbert MT, Lund O, Wesolowska A, Karmin M, Weinert LA, Wang B, Li J, Tai S, Xiao F, Hanihara T, van Driem G, Jha AR, Ricaut FX, de Knijff P, Migliano AB, Gallego Romero I, Kristiansen K, Lambert DM, Brunak S, Forster P, Brinkmann B, Nehlich O, Bunce M, Richards M, Gupta R, Bustamante CD, Krogh A, Foley RA, Lahr MM, Balloux F, Sicheritz-Pontén T, Villems R, Nielsen R, Wang J, Willerslev E. Rasmussen M, et al. Among authors: skotte l. Science. 2011 Oct 7;334(6052):94-8. doi: 10.1126/science.1211177. Epub 2011 Sep 22. Science. 2011. PMID: 21940856 Free PMC article.
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.
Albrechtsen A, Grarup N, Li Y, Sparsø T, Tian G, Cao H, Jiang T, Kim SY, Korneliussen T, Li Q, Nie C, Wu R, Skotte L, Morris AP, Ladenvall C, Cauchi S, Stančáková A, Andersen G, Astrup A, Banasik K, Bennett AJ, Bolund L, Charpentier G, Chen Y, Dekker JM, Doney AS, Dorkhan M, Forsen T, Frayling TM, Groves CJ, Gui Y, Hallmans G, Hattersley AT, He K, Hitman GA, Holmkvist J, Huang S, Jiang H, Jin X, Justesen JM, Kristiansen K, Kuusisto J, Lajer M, Lantieri O, Li W, Liang H, Liao Q, Liu X, Ma T, Ma X, Manijak MP, Marre M, Mokrosiński J, Morris AD, Mu B, Nielsen AA, Nijpels G, Nilsson P, Palmer CN, Rayner NW, Renström F, Ribel-Madsen R, Robertson N, Rolandsson O, Rossing P, Schwartz TW; D.E.S.I.R. Study Group; Slagboom PE, Sterner M; DIAGRAM Consortium; Tang M, Tarnow L, Tuomi T, van't Riet E, van Leeuwen N, Varga TV, Vestmar MA, Walker M, Wang B, Wang Y, Wu H, Xi F, Yengo L, Yu C, Zhang X, Zhang J, Zhang Q, Zhang W, Zheng H, Zhou Y, Altshuler D, 't Hart LM, Franks PW, Balkau B, Froguel P, McCarthy MI, Laakso M, Groop L, Christensen C, Brandslund I, Lauritzen T, Witte DR, Linneberg A, Jørgensen T, Hansen T, Wang J, Nielsen R, Pedersen O. Albrechtsen A, et al. Among authors: skotte l. Diabetologia. 2013 Feb;56(2):298-310. doi: 10.1007/s00125-012-2756-1. Epub 2012 Nov 19. Diabetologia. 2013. PMID: 23160641 Free PMC article.
The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders.
Andersen MK, Jørsboe E, Skotte L, Hanghøj K, Sandholt CH, Moltke I, Grarup N, Kern T, Mahendran Y, Søborg B, Bjerregaard P, Larsen CVL, Dahl-Petersen IK, Tiwari HK, Feenstra B, Koch A, Wiener HW, Hopkins SE, Pedersen O, Melbye M, Boyer BB, Jørgensen ME, Albrechtsen A, Hansen T. Andersen MK, et al. Among authors: skotte l. PLoS Genet. 2020 Jan 24;16(1):e1008544. doi: 10.1371/journal.pgen.1008544. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31978080 Free PMC article.
Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts.
Andersen MK, Skotte L, Jørsboe E, Polito R, Stæger FF, Aldiss P, Hanghøj K, Waples RK, Santander CG, Grarup N, Dahl-Petersen IK, Diaz LJ, Overvad M, Senftleber NK, Søborg B, Larsen CVL, Lemoine C, Pedersen O, Feenstra B, Bjerregaard P, Melbye M, Jørgensen ME, Færgeman NJ, Koch A, Moritz T, Gillum MP, Moltke I, Hansen T, Albrechtsen A. Andersen MK, et al. Among authors: skotte l. Gastroenterology. 2022 Apr;162(4):1171-1182.e3. doi: 10.1053/j.gastro.2021.12.236. Epub 2021 Dec 13. Gastroenterology. 2022. PMID: 34914943 Free article.
An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention.
Jørsboe E, Andersen MK, Skotte L, Stæger FF, Færgeman NJ, Hanghøj K, Santander CG, Senftleber NK, Diaz LJ, Overvad M, Waples RK, Geller F, Bjerregaard P, Melbye M, Larsen CVL, Feenstra B, Anders Koch, Jørgensen ME, Grarup N, Moltke I, Albrechtsen A, Hansen T. Jørsboe E, et al. Among authors: skotte l. HGG Adv. 2022 Jun 9;3(4):100118. doi: 10.1016/j.xhgg.2022.100118. eCollection 2022 Oct 13. HGG Adv. 2022. PMID: 36267056 Free PMC article.
35 results