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High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts.
Maciej-Hulme ML, Leprince ACN, Lavin A, Guimond SE, Turnbull JE, Pelletier J, Yates EA, Powell AK, Skidmore MA. Maciej-Hulme ML, et al. Among authors: skidmore ma. Anal Methods. 2023 Mar 16;15(11):1461-1469. doi: 10.1039/d2ay01803a. Anal Methods. 2023. PMID: 36876452 Free PMC article.
Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution.
Guimond SE, Rudd TR, Skidmore MA, Ori A, Gaudesi D, Cosentino C, Guerrini M, Edge R, Collison D, McInnes E, Torri G, Turnbull JE, Fernig DG, Yates EA. Guimond SE, et al. Among authors: skidmore ma. Biochemistry. 2009 Jun 9;48(22):4772-9. doi: 10.1021/bi802318z. Biochemistry. 2009. PMID: 19400583
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Rudd TR, Uniewicz KA, Ori A, Guimond SE, Skidmore MA, Gaudesi D, Xu R, Turnbull JE, Guerrini M, Torri G, Siligardi G, Wilkinson MC, Fernig DG, Yates EA. Rudd TR, et al. Among authors: skidmore ma. Org Biomol Chem. 2010 Dec 7;8(23):5390-7. doi: 10.1039/c0ob00246a. Epub 2010 Sep 3. Org Biomol Chem. 2010. PMID: 20865198
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