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Antiproliferation and Antiencystation Effect of Class II Histone Deacetylase Inhibitors on Acanthamoeba castellanii.
ACS Infect Dis. 2022 Feb 11;8(2):271-279. doi: 10.1021/acsinfecdis.1c00390. Epub 2022 Jan 7.
ACS Infect Dis. 2022.
PMID: 34994538
Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups.
Reßing N, Sönnichsen M, Osko JD, Schöler A, Schliehe-Diecks J, Skerhut A, Borkhardt A, Hauer J, Kassack MU, Christianson DW, Bhatia S, Hansen FK.
Reßing N, et al. Among authors: skerhut a.
J Med Chem. 2020 Sep 24;63(18):10339-10351. doi: 10.1021/acs.jmedchem.9b01888. Epub 2020 Sep 1.
J Med Chem. 2020.
PMID: 32803970
Free PMC article.
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5-(Trifluoromethyl)-1,2,4-oxadiazole (TFMO)-based highly selective class IIa HDAC inhibitors exhibit synergistic anticancer activity in combination with bortezomib.
Asfaha Y, Bollmann LM, Skerhut AJ, Fischer F, Horstick N, Roth D, Wecker M, Mammen C, Smits SHJ, Fluegen G, Kassack MU, Kurz T.
Asfaha Y, et al. Among authors: skerhut aj.
Eur J Med Chem. 2024 Jan 5;263:115907. doi: 10.1016/j.ejmech.2023.115907. Epub 2023 Nov 10.
Eur J Med Chem. 2024.
PMID: 37979441
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The Novel Class IIa Selective Histone Deacetylase Inhibitor YAK540 Is Synergistic with Bortezomib in Leukemia Cell Lines.
Bollmann LM, Skerhut AJ, Asfaha Y, Horstick N, Hanenberg H, Hamacher A, Kurz T, Kassack MU.
Bollmann LM, et al. Among authors: skerhut aj.
Int J Mol Sci. 2022 Nov 2;23(21):13398. doi: 10.3390/ijms232113398.
Int J Mol Sci. 2022.
PMID: 36362189
Free PMC article.
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