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Gelofusine Ameliorates Colistin-Induced Nephrotoxicity.
Antimicrob Agents Chemother. 2017 Nov 22;61(12):e00985-17. doi: 10.1128/AAC.00985-17. Print 2017 Dec.
Antimicrob Agents Chemother. 2017.
PMID: 28923868
Free PMC article.
Pharmacokinetics of the Individual Major Components of Polymyxin B and Colistin in Rats.
Sivanesan S, Roberts K, Wang J, Chea SE, Thompson PE, Li J, Nation RL, Velkov T.
Sivanesan S, et al.
J Nat Prod. 2017 Jan 27;80(1):225-229. doi: 10.1021/acs.jnatprod.6b01176. Epub 2017 Jan 12.
J Nat Prod. 2017.
PMID: 28080060
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Methionine Ameliorates Polymyxin-Induced Nephrotoxicity by Attenuating Cellular Oxidative Stress.
Azad MAK, Sivanesan S, Wang J, Chen K, Nation RL, Thompson PE, Roberts KD, Velkov T, Li J.
Azad MAK, et al.
Antimicrob Agents Chemother. 2017 Dec 21;62(1):e01254-17. doi: 10.1128/AAC.01254-17. Print 2018 Jan.
Antimicrob Agents Chemother. 2017.
PMID: 29061752
Free PMC article.
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Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.
Velkov T, Deris ZZ, Huang JX, Azad MA, Butler M, Sivanesan S, Kaminskas LM, Dong YD, Boyd B, Baker MA, Cooper MA, Nation RL, Li J.
Velkov T, et al.
Innate Immun. 2014 May;20(4):350-63. doi: 10.1177/1753425913493337. Epub 2013 Jul 25.
Innate Immun. 2014.
PMID: 23887184
Free PMC article.
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A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity.
Deris ZZ, Akter J, Sivanesan S, Roberts KD, Thompson PE, Nation RL, Li J, Velkov T.
Deris ZZ, et al.
J Antibiot (Tokyo). 2014 Feb;67(2):147-51. doi: 10.1038/ja.2013.111. Epub 2013 Oct 30.
J Antibiot (Tokyo). 2014.
PMID: 24169795
Free PMC article.
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Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.
Velkov T, Gallardo-Godoy A, Swarbrick JD, Blaskovich MAT, Elliott AG, Han M, Thompson PE, Roberts KD, Huang JX, Becker B, Butler MS, Lash LH, Henriques ST, Nation RL, Sivanesan S, Sani MA, Separovic F, Mertens H, Bulach D, Seemann T, Owen J, Li J, Cooper MA.
Velkov T, et al.
Cell Chem Biol. 2018 Apr 19;25(4):380-391.e5. doi: 10.1016/j.chembiol.2018.01.005. Epub 2018 Feb 3.
Cell Chem Biol. 2018.
PMID: 29396290
Free PMC article.
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Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes.
Han ML, Shen HH, Hansford KA, Schneider EK, Sivanesan S, Roberts KD, Thompson PE, Le Brun AP, Zhu Y, Sani MA, Separovic F, Blaskovich MAT, Baker MA, Moskowitz SM, Cooper MA, Li J, Velkov T.
Han ML, et al.
ACS Infect Dis. 2017 Aug 11;3(8):606-619. doi: 10.1021/acsinfecdis.7b00065. Epub 2017 Jul 11.
ACS Infect Dis. 2017.
PMID: 28695731
Free PMC article.
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The RNA-dependent-RNA polymerase, an emerging antiviral drug target for the Hendra virus.
Velkov T, Carbone V, Akter J, Sivanesan S, Li J, Beddoe T, Marsh GA.
Velkov T, et al.
Curr Drug Targets. 2014 Jan;15(1):103-13. doi: 10.2174/1389450114888131204163210.
Curr Drug Targets. 2014.
PMID: 24102407
Review.
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