Sivalingam J - Search Results

1

Multidimensional Genome-wide Analyses Show Accurate FVIII Integration by ZFN in Primary Human Cells.

Sivalingam J, Kenanov D, Han H, Nirmal AJ, Ng WH, Lee SS, Masilamani J, Phan TT, Maurer-Stroh S, Kon OL. Sivalingam J, et al. Mol Ther. 2016 Mar;24(3):607-19. doi: 10.1038/mt.2015.223. Epub 2015 Dec 22. Mol Ther. 2016. PMID: 26689265 Free PMC article.

2

Biosafety assessment of site-directed transgene integration in human umbilical cord-lining cells.

Sivalingam J, Krishnan S, Ng WH, Lee SS, Phan TT, Kon OL. Sivalingam J, et al. Mol Ther. 2010 Jul;18(7):1346-56. doi: 10.1038/mt.2010.61. Epub 2010 Apr 27. Mol Ther. 2010. PMID: 20424600 Free PMC article.

3

Integrated Multimodal Evaluation of Genotoxicity in ZFN-Modified Primary Human Cells.

Sivalingam J, Kenanov D, Ng WH, Lee SS, Phan TT, Maurer-Stroh S, Kon OL. Sivalingam J, et al. Methods Mol Biol. 2018;1867:141-164. doi: 10.1007/978-1-4939-8799-3_11. Methods Mol Biol. 2018. PMID: 30155821

4

Intragenic integration in DLC1 sustains factor VIII expression in primary human cells without insertional oncogenicity.

Sivalingam J, Phan TT, Kon OL. Sivalingam J, et al. Gene Ther. 2014 Apr;21(4):402-12. doi: 10.1038/gt.2014.11. Epub 2014 Feb 20. Gene Ther. 2014. PMID: 24553346 Free PMC article.

5

Durable engraftment of genetically modified FVIII-secreting autologous bone marrow stromal cells in the intramedullary microenvironment.

Lee SS, Sivalingam J, Nirmal AJ, Ng WH, Kee I, Song IC, Kiong CY, Gales KA, Chua F, Pena EM, Ogden BE, Kon OL. Lee SS, et al. Among authors: sivalingam j. J Cell Mol Med. 2018 Jul;22(7):3698-3702. doi: 10.1111/jcmm.13648. Epub 2018 Apr 23. J Cell Mol Med. 2018. PMID: 29682884 Free PMC article.

6

Plasmid-electroporated primary hepatocytes acquire quasi-physiological secretion of human insulin and restore euglycemia in diabetic mice.

Chen NK, Sivalingam J, Tan SY, Kon OL. Chen NK, et al. Among authors: sivalingam j. Gene Ther. 2005 Apr;12(8):655-67. doi: 10.1038/sj.gt.3302446. Gene Ther. 2005. PMID: 15703765

7

Nonvirally modified autologous primary hepatocytes correct diabetes and prevent target organ injury in a large preclinical model.

Chen NK, Wong JS, Kee IH, Lai SH, Thng CH, Ng WH, Ng RT, Tan SY, Lee SY, Tan ME, Sivalingam J, Chow PK, Kon OL. Chen NK, et al. Among authors: sivalingam j. PLoS One. 2008 Mar 5;3(3):e1734. doi: 10.1371/journal.pone.0001734. PLoS One. 2008. PMID: 18320053 Free PMC article.

8

Superior Red Blood Cell Generation from Human Pluripotent Stem Cells Through a Novel Microcarrier-Based Embryoid Body Platform.

Sivalingam J, Lam AT, Chen HY, Yang BX, Chen AK, Reuveny S, Loh YH, Oh SK. Sivalingam J, et al. Tissue Eng Part C Methods. 2016 Aug;22(8):765-80. doi: 10.1089/ten.TEC.2015.0579. Epub 2016 Aug 1. Tissue Eng Part C Methods. 2016. PMID: 27392822

9

Review: In vitro generation of red blood cells for transfusion medicine: Progress, prospects and challenges.

Lee E, Sivalingam J, Lim ZR, Chia G, Shi LG, Roberts M, Loh YH, Reuveny S, Oh SK. Lee E, et al. Among authors: sivalingam j. Biotechnol Adv. 2018 Dec;36(8):2118-2128. doi: 10.1016/j.biotechadv.2018.09.006. Epub 2018 Sep 29. Biotechnol Adv. 2018. PMID: 30273713 Review.

10

A Scalable Suspension Platform for Generating High-Density Cultures of Universal Red Blood Cells from Human Induced Pluripotent Stem Cells.

Sivalingam J, SuE Y, Lim ZR, Lam ATL, Lee AP, Lim HL, Chen HY, Tan HK, Warrier T, Hang JW, Nazir NB, Tan AHM, Renia L, Loh YH, Reuveny S, Malleret B, Oh SKW. Sivalingam J, et al. Stem Cell Reports. 2021 Jan 12;16(1):182-197. doi: 10.1016/j.stemcr.2020.11.008. Epub 2020 Dec 10. Stem Cell Reports. 2021. PMID: 33306988 Free PMC article.

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