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Disrupted Binding of Cystathionine γ-Lyase to p53 Promotes Endothelial Senescence.
Hu J, Leisegang MS, Looso M, Drekolia MK, Wittig J, Mettner J, Karantanou C, Kyselova A, Dumbovic G, Li X, Li Y, Guenther S, John D, Siragusa M, Zukunft S, Oo JA, Wittig I, Hille S, Weigert A, Knapp S, Brandes RP, Müller OJ, Papapetropoulos A, Sigala F, Dobreva G, Kojonazarov B, Fleming I, Bibli SI. Hu J, et al. Among authors: siragusa m. Circ Res. 2023 Oct 27;133(10):842-857. doi: 10.1161/CIRCRESAHA.123.323084. Epub 2023 Oct 6. Circ Res. 2023. PMID: 37800327
Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis.
Bibli SI, Hu J, Sigala F, Wittig I, Heidler J, Zukunft S, Tsilimigras DI, Randriamboavonjy V, Wittig J, Kojonazarov B, Schürmann C, Siragusa M, Siuda D, Luck B, Abdel Malik R, Filis KA, Zografos G, Chen C, Wang DW, Pfeilschifter J, Brandes RP, Szabo C, Papapetropoulos A, Fleming I. Bibli SI, et al. Among authors: siragusa m. Circulation. 2019 Jan 2;139(1):101-114. doi: 10.1161/CIRCULATIONAHA.118.034757. Circulation. 2019. PMID: 29970364 Free article.
Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice.
Malacarne PF, Ratiu C, Gajos-Draus A, Müller N, Lopez M, Pflüger-Müller B, Ding X, Warwick T, Oo J, Siragusa M, Angioni C, Günther S, Weigert A, Geißlinger G, Lütjohann D, Schunck WH, Fleming I, Brandes RP, Rezende F. Malacarne PF, et al. Among authors: siragusa m. Hypertension. 2022 Jun;79(6):1216-1226. doi: 10.1161/HYPERTENSIONAHA.121.18752. Epub 2022 Mar 31. Hypertension. 2022. PMID: 35354305
Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition.
Siragusa M, Thöle J, Bibli SI, Luck B, Loot AE, de Silva K, Wittig I, Heidler J, Stingl H, Randriamboavonjy V, Kohlstedt K, Brüne B, Weigert A, Fisslthaler B, Fleming I. Siragusa M, et al. EMBO J. 2019 Sep 2;38(17):e100938. doi: 10.15252/embj.2018100938. Epub 2019 Jul 22. EMBO J. 2019. PMID: 31328803 Free PMC article.
Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.
Iring A, Jin YJ, Albarrán-Juárez J, Siragusa M, Wang S, Dancs PT, Nakayama A, Tonack S, Chen M, Künne C, Sokol AM, Günther S, Martínez A, Fleming I, Wettschureck N, Graumann J, Weinstein LS, Offermanns S. Iring A, et al. Among authors: siragusa m. J Clin Invest. 2019 Jun 17;129(7):2775-2791. doi: 10.1172/JCI123825. eCollection 2019 Jun 17. J Clin Invest. 2019. PMID: 31205027 Free PMC article.
135 results