Sinnis P - Search Results

1

A cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic development.

Lehmann C, Heitmann A, Mishra S, Burda PC, Singer M, Prado M, Niklaus L, Lacroix C, Ménard R, Frischknecht F, Stanway R, Sinnis P, Heussler V. Lehmann C, et al. Among authors: sinnis p. PLoS Pathog. 2014 Aug 28;10(8):e1004336. doi: 10.1371/journal.ppat.1004336. eCollection 2014 Aug. PLoS Pathog. 2014. PMID: 25166051 Free PMC article.

2

The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.

Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, Sidhu AB, Purcell LA, Gratraud P, Kremer L, Waters AP, Schiehser G, Jacobus DP, Janse CJ, Ager A, Jacobs WR Jr, Sacchettini JC, Heussler V, Sinnis P, Fidock DA. Yu M, et al. Among authors: sinnis p. Cell Host Microbe. 2008 Dec 11;4(6):567-78. doi: 10.1016/j.chom.2008.11.001. Cell Host Microbe. 2008. PMID: 19064257 Free PMC article.

3

Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo.

Cockburn IA, Tse SW, Radtke AJ, Srinivasan P, Chen YC, Sinnis P, Zavala F. Cockburn IA, et al. Among authors: sinnis p. PLoS Pathog. 2011 Mar;7(3):e1001318. doi: 10.1371/journal.ppat.1001318. Epub 2011 Mar 17. PLoS Pathog. 2011. PMID: 21445239 Free PMC article.

4

Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole.

Vera IM, Beatty WL, Sinnis P, Kim K. Vera IM, et al. Among authors: sinnis p. PLoS Pathog. 2011 Sep;7(9):e1002197. doi: 10.1371/journal.ppat.1002197. Epub 2011 Sep 1. PLoS Pathog. 2011. PMID: 21909259 Free PMC article.

5

Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity.

Ejigiri I, Ragheb DR, Pino P, Coppi A, Bennett BL, Soldati-Favre D, Sinnis P. Ejigiri I, et al. Among authors: sinnis p. PLoS Pathog. 2012;8(7):e1002725. doi: 10.1371/journal.ppat.1002725. Epub 2012 Jul 26. PLoS Pathog. 2012. PMID: 22911675 Free PMC article.

6

Quantification of sporozoite invasion, migration, and development by microscopy and flow cytometry.

Sinnis P, De La Vega P, Coppi A, Krzych U, Mota MM. Sinnis P, et al. Methods Mol Biol. 2013;923:385-400. doi: 10.1007/978-1-62703-026-7_27. Methods Mol Biol. 2013. PMID: 22990793 Free PMC article.

7

A key role for lipoic acid synthesis during Plasmodium liver stage development.

Falkard B, Kumar TR, Hecht LS, Matthews KA, Henrich PP, Gulati S, Lewis RE, Manary MJ, Winzeler EA, Sinnis P, Prigge ST, Heussler V, Deschermeier C, Fidock D. Falkard B, et al. Among authors: sinnis p. Cell Microbiol. 2013 Sep;15(9):1585-604. doi: 10.1111/cmi.12137. Epub 2013 Apr 5. Cell Microbiol. 2013. PMID: 23490300 Free PMC article.

8

The repeat region of the circumsporozoite protein is critical for sporozoite formation and maturation in Plasmodium.

Ferguson DJ, Balaban AE, Patzewitz EM, Wall RJ, Hopp CS, Poulin B, Mohmmed A, Malhotra P, Coppi A, Sinnis P, Tewari R. Ferguson DJ, et al. Among authors: sinnis p. PLoS One. 2014 Dec 1;9(12):e113923. doi: 10.1371/journal.pone.0113923. eCollection 2014. PLoS One. 2014. PMID: 25438048 Free PMC article.

9

Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses.

Radtke AJ, Kastenmüller W, Espinosa DA, Gerner MY, Tse SW, Sinnis P, Germain RN, Zavala FP, Cockburn IA. Radtke AJ, et al. Among authors: sinnis p. PLoS Pathog. 2015 Feb 6;11(2):e1004637. doi: 10.1371/journal.ppat.1004637. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25658939 Free PMC article.

10

Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies.

Espinosa DA, Gutierrez GM, Rojas-López M, Noe AR, Shi L, Tse SW, Sinnis P, Zavala F. Espinosa DA, et al. Among authors: sinnis p. J Infect Dis. 2015 Oct 1;212(7):1111-9. doi: 10.1093/infdis/jiv154. Epub 2015 Mar 11. J Infect Dis. 2015. PMID: 25762791 Free PMC article.

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