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Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity.
Iqbal F, Schlotter F, Becker-Greene D, Lupieri A, Goettsch C, Hutcheson JD, Rogers MA, Itoh S, Halu A, Lee LH, Blaser MC, Mlynarchik AK, Hagita S, Kuraoka S, Chen HY, Engert JC, Passos LSA, Jha PK, Osborn EA, Jaffer FA, Body SC, Robson SC, Thanassoulis G, Aikawa M, Singh SA, Sonawane AR, Aikawa E. Iqbal F, et al. Among authors: singh sa. Eur Heart J. 2023 Mar 7;44(10):885-898. doi: 10.1093/eurheartj/ehac818. Eur Heart J. 2023. PMID: 36660854 Free PMC article.
New CETP inhibitor K-312 reduces PCSK9 expression: a potential effect on LDL cholesterol metabolism.
Miyosawa K, Watanabe Y, Murakami K, Murakami T, Shibata H, Iwashita M, Yamazaki H, Yamazaki K, Ohgiya T, Shibuya K, Mizuno K, Tanabe S, Singh SA, Aikawa M. Miyosawa K, et al. Among authors: singh sa. Am J Physiol Endocrinol Metab. 2015 Jul 15;309(2):E177-90. doi: 10.1152/ajpendo.00528.2014. Epub 2015 May 26. Am J Physiol Endocrinol Metab. 2015. PMID: 26015437 Free article.
Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.
Goettsch C, Hutcheson JD, Aikawa M, Iwata H, Pham T, Nykjaer A, Kjolby M, Rogers M, Michel T, Shibasaki M, Hagita S, Kramann R, Rader DJ, Libby P, Singh SA, Aikawa E. Goettsch C, et al. Among authors: singh sa. J Clin Invest. 2016 Apr 1;126(4):1323-36. doi: 10.1172/JCI80851. Epub 2016 Mar 7. J Clin Invest. 2016. PMID: 26950419 Free PMC article.
Endophenotype Network Models: Common Core of Complex Diseases.
Ghiassian SD, Menche J, Chasman DI, Giulianini F, Wang R, Ricchiuto P, Aikawa M, Iwata H, Müller C, Zeller T, Sharma A, Wild P, Lackner K, Singh S, Ridker PM, Blankenberg S, Barabási AL, Loscalzo J. Ghiassian SD, et al. Sci Rep. 2016 Jun 9;6:27414. doi: 10.1038/srep27414. Sci Rep. 2016. PMID: 27278246 Free PMC article.
241 results