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An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy.
Khalil BD, Sanchez R, Rahman T, Rodriguez-Tirado C, Moritsch S, Martinez AR, Miles B, Farias E, Mezei M, Nobre AR, Singh D, Kale N, Sproll KC, Sosa MS, Aguirre-Ghiso JA. Khalil BD, et al. Among authors: singh d. J Exp Med. 2022 Jan 3;219(1):e20210836. doi: 10.1084/jem.20210836. Epub 2021 Nov 23. J Exp Med. 2022. PMID: 34812843 Free PMC article.
Bone marrow NG2+/Nestin+ mesenchymal stem cells drive DTC dormancy via TGFβ2.
Nobre AR, Risson E, Singh DK, Di Martino JS, Cheung JF, Wang J, Johnson J, Russnes HG, Bravo-Cordero JJ, Birbrair A, Naume B, Azhar M, Frenette PS, Aguirre-Ghiso JA. Nobre AR, et al. Nat Cancer. 2021 Mar;2(3):327-339. doi: 10.1038/s43018-021-00179-8. Epub 2021 Mar 11. Nat Cancer. 2021. PMID: 34993493 Free PMC article.
Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells.
Borriello L, Coste A, Traub B, Sharma VP, Karagiannis GS, Lin Y, Wang Y, Ye X, Duran CL, Chen X, Friedman M, Sosa MS, Sun D, Dalla E, Singh DK, Oktay MH, Aguirre-Ghiso JA, Condeelis JS, Entenberg D. Borriello L, et al. Among authors: singh dk. Nat Commun. 2022 Feb 2;13(1):626. doi: 10.1038/s41467-022-28076-3. Nat Commun. 2022. PMID: 35110548 Free PMC article.
Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage.
Connolly SJ, Sharma M, Cohen AT, Demchuk AM, Członkowska A, Lindgren AG, Molina CA, Bereczki D, Toni D, Seiffge DJ, Tanne D, Sandset EC, Tsivgoulis G, Christensen H, Beyer-Westendorf J, Coutinho JM, Crowther M, Verhamme P, Amarenco P, Roine RO, Mikulik R, Lemmens R, Veltkamp R, Middeldorp S, Robinson TG, Milling TJ Jr, Tedim-Cruz V, Lang W, Himmelmann A, Ladenvall P, Knutsson M, Ekholm E, Law A, Taylor A, Karyakina T, Xu L, Tsiplova K, Poli S, Kallmünzer B, Gumbinger C, Shoamanesh A; ANNEXA-I Investigators. Connolly SJ, et al. N Engl J Med. 2024 May 16;390(19):1745-1755. doi: 10.1056/NEJMoa2313040. N Engl J Med. 2024. PMID: 38749032 Clinical Trial.
7,636 results