Singh A - Search Results

1

Phagosomal Copper-Promoted Oxidative Attack on Intracellular Mycobacterium tuberculosis.

Libardo MDJ, de la Fuente-Nuñez C, Anand K, Krishnamoorthy G, Kaiser P, Pringle SC, Dietz C, Pierce S, Smith MB, Barczak A, Kaufmann SHE, Singh A, Angeles-Boza AM. Libardo MDJ, et al. Among authors: singh a. ACS Infect Dis. 2018 Nov 9;4(11):1623-1634. doi: 10.1021/acsinfecdis.8b00171. Epub 2018 Sep 6. ACS Infect Dis. 2018. PMID: 30141623

2

Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide.

Tyagi P, Dharmaraja AT, Bhaskar A, Chakrapani H, Singh A. Tyagi P, et al. Among authors: singh a. Free Radic Biol Med. 2015 Jul;84:344-354. doi: 10.1016/j.freeradbiomed.2015.03.008. Epub 2015 Mar 27. Free Radic Biol Med. 2015. PMID: 25819161 Free PMC article.

3

Mycobacterium tuberculosis WhiB3 Responds to Vacuolar pH-induced Changes in Mycothiol Redox Potential to Modulate Phagosomal Maturation and Virulence.

Mehta M, Rajmani RS, Singh A. Mehta M, et al. Among authors: singh a. J Biol Chem. 2016 Feb 5;291(6):2888-903. doi: 10.1074/jbc.M115.684597. Epub 2015 Dec 4. J Biol Chem. 2016. PMID: 26637353 Free PMC article.

4

Identifying and Tackling Emergent Vulnerability in Drug-Resistant Mycobacteria.

Padiadpu J, Baloni P, Anand K, Munshi M, Thakur C, Mohan A, Singh A, Chandra N. Padiadpu J, et al. Among authors: singh a. ACS Infect Dis. 2016 Sep 9;2(9):592-607. doi: 10.1021/acsinfecdis.6b00004. Epub 2016 Aug 8. ACS Infect Dis. 2016. PMID: 27759382

5

Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis.

Mishra S, Shukla P, Bhaskar A, Anand K, Baloni P, Jha RK, Mohan A, Rajmani RS, Nagaraja V, Chandra N, Singh A. Mishra S, et al. Among authors: singh a. Elife. 2017 May 26;6:e25624. doi: 10.7554/eLife.25624. Elife. 2017. PMID: 28548640 Free PMC article.

6

Multifaceted remodeling by vitamin C boosts sensitivity of Mycobacterium tuberculosis subpopulations to combination treatment by anti-tubercular drugs.

Sikri K, Duggal P, Kumar C, Batra SD, Vashist A, Bhaskar A, Tripathi K, Sethi T, Singh A, Tyagi JS. Sikri K, et al. Among authors: singh a. Redox Biol. 2018 May;15:452-466. doi: 10.1016/j.redox.2017.12.020. Epub 2018 Jan 3. Redox Biol. 2018. PMID: 29413958 Free PMC article.

7

Redox-dependent condensation of the mycobacterial nucleoid by WhiB4.

Chawla M, Mishra S, Anand K, Parikh P, Mehta M, Vij M, Verma T, Singh P, Jakkala K, Verma HN, AjitKumar P, Ganguli M, Narain Seshasayee AS, Singh A. Chawla M, et al. Among authors: singh a, singh p. Redox Biol. 2018 Oct;19:116-133. doi: 10.1016/j.redox.2018.08.006. Epub 2018 Aug 13. Redox Biol. 2018. PMID: 30149290 Free PMC article.

8

Mycobacterium tuberculosis WhiB3 maintains redox homeostasis and survival in response to reactive oxygen and nitrogen species.

Mehta M, Singh A. Mehta M, et al. Among authors: singh a. Free Radic Biol Med. 2019 Feb 1;131:50-58. doi: 10.1016/j.freeradbiomed.2018.11.032. Epub 2018 Nov 27. Free Radic Biol Med. 2019. PMID: 30500421 Free PMC article.

9

Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis.

Mishra R, Kohli S, Malhotra N, Bandyopadhyay P, Mehta M, Munshi M, Adiga V, Ahuja VK, Shandil RK, Rajmani RS, Seshasayee ASN, Singh A. Mishra R, et al. Among authors: singh a. Sci Transl Med. 2019 Nov 13;11(518):eaaw6635. doi: 10.1126/scitranslmed.aaw6635. Sci Transl Med. 2019. PMID: 31723039 Free PMC article.

10

Mycobacterium tuberculosis Reactivates HIV-1 via Exosome-Mediated Resetting of Cellular Redox Potential and Bioenergetics.

Tyagi P, Pal VK, Agrawal R, Singh S, Srinivasan S, Singh A. Tyagi P, et al. Among authors: singh s, singh a. mBio. 2020 Mar 3;11(2):e03293-19. doi: 10.1128/mBio.03293-19. mBio. 2020. PMID: 32127457 Free PMC article.

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