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Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities.
Garofano L, Migliozzi S, Oh YT, D'Angelo F, Najac RD, Ko A, Frangaj B, Caruso FP, Yu K, Yuan J, Zhao W, Di Stefano AL, Bielle F, Jiang T, Sims P, Suvà ML, Tang F, Su XD, Ceccarelli M, Sanson M, Lasorella A, Iavarone A. Garofano L, et al. Among authors: sims p. Nat Cancer. 2021 Feb;2(2):141-156. doi: 10.1038/s43018-020-00159-4. Epub 2021 Jan 11. Nat Cancer. 2021. PMID: 33681822 Free PMC article.
The transcriptional regulatory network of proneural glioma determines the genetic alterations selected during tumor progression.
Sonabend AM, Bansal M, Guarnieri P, Lei L, Amendolara B, Soderquist C, Leung R, Yun J, Kennedy B, Sisti J, Bruce S, Bruce R, Shakya R, Ludwig T, Rosenfeld S, Sims PA, Bruce JN, Califano A, Canoll P. Sonabend AM, et al. Among authors: sims pa. Cancer Res. 2014 Mar 1;74(5):1440-1451. doi: 10.1158/0008-5472.CAN-13-2150. Epub 2014 Jan 3. Cancer Res. 2014. PMID: 24390738 Free PMC article.
SPOTs fill a major gap in RNA quantification.
Yuan J, Sims PA. Yuan J, et al. Nat Methods. 2017 Nov 30;14(12):1137-1138. doi: 10.1038/nmeth.4515. Nat Methods. 2017. PMID: 29190269 No abstract available.
Single-cell transcriptome analysis of lineage diversity in high-grade glioma.
Yuan J, Levitin HM, Frattini V, Bush EC, Boyett DM, Samanamud J, Ceccarelli M, Dovas A, Zanazzi G, Canoll P, Bruce JN, Lasorella A, Iavarone A, Sims PA. Yuan J, et al. Among authors: sims pa. Genome Med. 2018 Jul 24;10(1):57. doi: 10.1186/s13073-018-0567-9. Genome Med. 2018. PMID: 30041684 Free PMC article.
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma.
Zhao J, Chen AX, Gartrell RD, Silverman AM, Aparicio L, Chu T, Bordbar D, Shan D, Samanamud J, Mahajan A, Filip I, Orenbuch R, Goetz M, Yamaguchi JT, Cloney M, Horbinski C, Lukas RV, Raizer J, Rae AI, Yuan J, Canoll P, Bruce JN, Saenger YM, Sims P, Iwamoto FM, Sonabend AM, Rabadan R. Zhao J, et al. Among authors: sims p. Nat Med. 2019 Mar;25(3):462-469. doi: 10.1038/s41591-019-0349-y. Epub 2019 Feb 11. Nat Med. 2019. PMID: 30742119 Free PMC article.
620 results