Sims J - Search Results

1

Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell-mediated antitumor immune response.

De Gassart A, Le KS, Brune P, Agaugué S, Sims J, Goubard A, Castellano R, Joalland N, Scotet E, Collette Y, Valentin E, Ghigo C, Pasero C, Colazet M, Guillén J, Cano CE, Marabelle A, De Bonno J, Hoet R, Truneh A, Olive D, Frohna P. De Gassart A, et al. Among authors: sims j. Sci Transl Med. 2021 Oct 20;13(616):eabj0835. doi: 10.1126/scitranslmed.abj0835. Epub 2021 Oct 20. Sci Transl Med. 2021. PMID: 34669444

2

Integrated pharmacokinetic, pharmacodynamic and immunogenicity profiling of an anti-CCL21 monoclonal antibody in cynomolgus monkeys.

Dudal S, Subramanian K, Flandre T, Law WS, Lowe PJ, Skerjanec A, Genin JC, Duval M, Piequet A, Cordier A, Jarai G, Van Heeke G, Taplin S, Krantz C, Jones S, Warren AP, Brennan FR, Sims J, Lloyd P. Dudal S, et al. Among authors: sims j. MAbs. 2015;7(5):829-37. doi: 10.1080/19420862.2015.1060384. MAbs. 2015. PMID: 26230385 Free PMC article.

3

On setting the first dose in man: quantitating biotherapeutic drug-target binding through pharmacokinetic and pharmacodynamic models.

Lowe PJ, Tannenbaum S, Wu K, Lloyd P, Sims J. Lowe PJ, et al. Among authors: sims j. Basic Clin Pharmacol Toxicol. 2010 Mar;106(3):195-209. doi: 10.1111/j.1742-7843.2009.00513.x. Epub 2009 Dec 29. Basic Clin Pharmacol Toxicol. 2010. PMID: 20050847 Free article. Review.

4

Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies.

Brennan FR, Morton LD, Spindeldreher S, Kiessling A, Allenspach R, Hey A, Muller PY, Frings W, Sims J. Brennan FR, et al. Among authors: sims j. MAbs. 2010 May-Jun;2(3):233-55. doi: 10.4161/mabs.2.3.11782. Epub 2010 May 23. MAbs. 2010. PMID: 20421713 Free PMC article. Review.

5

The minimum anticipated biological effect level (MABEL) for selection of first human dose in clinical trials with monoclonal antibodies.

Muller PY, Milton M, Lloyd P, Sims J, Brennan FR. Muller PY, et al. Among authors: sims j. Curr Opin Biotechnol. 2009 Dec;20(6):722-9. doi: 10.1016/j.copbio.2009.10.013. Epub 2009 Nov 5. Curr Opin Biotechnol. 2009. PMID: 19896825 Review.

6

Evaluation of dried blood spots for the quantification of therapeutic monoclonal antibodies and detection of anti-drug antibodies.

Kaendler K, Warren A, Lloyd P, Sims J, Sickert D. Kaendler K, et al. Among authors: sims j. Bioanalysis. 2013 Mar;5(5):613-22. doi: 10.4155/bio.13.11. Bioanalysis. 2013. PMID: 23425276

7

A whole blood in vitro cytokine release assay with aqueous monoclonal antibody presentation for the prediction of therapeutic protein induced cytokine release syndrome in humans.

Wolf B, Morgan H, Krieg J, Gani Z, Milicov A, Warncke M, Brennan F, Jones S, Sims J, Kiessling A. Wolf B, et al. Among authors: sims j. Cytokine. 2012 Dec;60(3):828-37. doi: 10.1016/j.cyto.2012.08.018. Epub 2012 Sep 15. Cytokine. 2012. PMID: 22986013

8

Waiving in vivo studies for monoclonal antibody biosimilar development: National and global challenges.

Chapman K, Adjei A, Baldrick P, da Silva A, De Smet K, DiCicco R, Hong SS, Jones D, Leach MW, McBlane J, Ragan I, Reddy P, Stewart DI, Suitters A, Sims J. Chapman K, et al. Among authors: sims j. MAbs. 2016;8(3):427-35. doi: 10.1080/19420862.2016.1145331. MAbs. 2016. PMID: 26854177 Free PMC article. Review.

9

The industry view on long-term toxicology testing in drug development of human pharmaceuticals.

Van Cauteren H, Bentley P, Bode G, Cordier A, Coussement W, Heining P, Sims J. Van Cauteren H, et al. Among authors: sims j. Pharmacol Toxicol. 2000;86 Suppl 1:1-5. doi: 10.1034/j.1600-0773.2000.d01-1.x. Pharmacol Toxicol. 2000. PMID: 10905744 Review.

10

Pharmacokinetics, metabolism and distribution of PEGs and PEGylated proteins: quo vadis?

Baumann A, Tuerck D, Prabhu S, Dickmann L, Sims J. Baumann A, et al. Among authors: sims j. Drug Discov Today. 2014 Oct;19(10):1623-31. doi: 10.1016/j.drudis.2014.06.002. Epub 2014 Jun 11. Drug Discov Today. 2014. PMID: 24929223 Review.

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