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GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao Y, Du Jiang P, Chao BN, Cagdas D, Kubo S, Balasubramaniyam A, Zhang Y, Shadur B, NaserEddin A, Folio LR, Schwarz B, Bohrnsen E, Zheng L, Lynberg M, Gottlieb S, Leney-Greene MA, Park AY, Tezcan I, Akdogan A, Gocmen R, Onder S, Rosenberg A, Soilleux EJ, Johnson E, Jackson PK, Demeter J, Chauvin SD, Paul F, Selbach M, Bulut H, Clatworthy MR, Tuong ZK, Zhang H, Stewart BJ, Bosio CM, Stepensky P, Clare S, Ganesan S, Pascall JC, Daumke O, Butcher GW, McMichael AJ, Simon AK, Lenardo MJ. Yao Y, et al. Among authors: simon ak. J Exp Med. 2022 Jun 6;219(6):e20201405. doi: 10.1084/jem.20201405. Epub 2022 May 13. J Exp Med. 2022. PMID: 35551368 Free PMC article.
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.
Mortensen M, Soilleux EJ, Djordjevic G, Tripp R, Lutteropp M, Sadighi-Akha E, Stranks AJ, Glanville J, Knight S, Jacobsen SE, Kranc KR, Simon AK. Mortensen M, et al. Among authors: simon ak. J Exp Med. 2011 Mar 14;208(3):455-67. doi: 10.1084/jem.20101145. Epub 2011 Feb 21. J Exp Med. 2011. PMID: 21339326 Free PMC article.
Autophagy is a critical regulator of memory CD8(+) T cell formation.
Puleston DJ, Zhang H, Powell TJ, Lipina E, Sims S, Panse I, Watson AS, Cerundolo V, Townsend AR, Klenerman P, Simon AK. Puleston DJ, et al. Among authors: simon ak. Elife. 2014 Nov 11;3:e03706. doi: 10.7554/eLife.03706. Elife. 2014. PMID: 25385531 Free PMC article.
Dual proteolytic pathways govern glycolysis and immune competence.
Lu W, Zhang Y, McDonald DO, Jing H, Carroll B, Robertson N, Zhang Q, Griffin H, Sanderson S, Lakey JH, Morgan NV, Reynard LN, Zheng L, Murdock HM, Turvey SE, Hackett SJ, Prestidge T, Hall JM, Cant AJ, Matthews HF, Koref MF, Simon AK, Korolchuk VI, Lenardo MJ, Hambleton S, Su HC. Lu W, et al. Among authors: simon ak. Cell. 2014 Dec 18;159(7):1578-90. doi: 10.1016/j.cell.2014.12.001. Cell. 2014. PMID: 25525876 Free PMC article.
Techniques for the Detection of Autophagy in Primary Mammalian Cells.
Puleston D, Phadwal K, Watson AS, Soilleux EJ, Chittaranjan S, Bortnik S, Gorski SM, Ktistakis N, Simon AK. Puleston D, et al. Among authors: simon ak. Cold Spring Harb Protoc. 2015 Sep 1;2015(9):pdb.top070391. doi: 10.1101/pdb.top070391. Cold Spring Harb Protoc. 2015. PMID: 26330629
Autophagy and Immune Senescence.
Zhang H, Puleston DJ, Simon AK. Zhang H, et al. Among authors: simon ak. Trends Mol Med. 2016 Aug;22(8):671-686. doi: 10.1016/j.molmed.2016.06.001. Epub 2016 Jul 7. Trends Mol Med. 2016. PMID: 27395769 Review.
117 results