Simmaco M - Search Results

1

Evaluation of Drug-Drug Interactions in EGFR-Mutated Non-Small-Cell Lung Cancer Patients during Treatment with Tyrosine-Kinase Inhibitors.

Occhipinti M, Brambilla M, Galli G, Manglaviti S, Giammaruco M, Prelaj A, Ferrara R, De Toma A, Proto C, Beninato T, Zattarin E, Lo Russo G, Gelibter AJ, Simmaco M, Preissner R, Garassino MC, De Braud F, Marchetti P. Occhipinti M, et al. Among authors: simmaco m. J Pers Med. 2021 May 18;11(5):424. doi: 10.3390/jpm11050424. J Pers Med. 2021. PMID: 34069851 Free PMC article.

2

Genotype-phenotype correlations in 5-fluorouracil metabolism: a candidate DPYD haplotype to improve toxicity prediction.

Gentile G, Botticelli A, Lionetto L, Mazzuca F, Simmaco M, Marchetti P, Borro M. Gentile G, et al. Among authors: simmaco m. Pharmacogenomics J. 2016 Aug;16(4):320-5. doi: 10.1038/tpj.2015.56. Epub 2015 Jul 28. Pharmacogenomics J. 2016. PMID: 26216193

3

Personalized Cancer Therapy Considering Cytochrome P450 Variability.

Preissner S, Simmaco M, Gentile G, Preissner R. Preissner S, et al. Among authors: simmaco m. Adv Pharmacol. 2015;74:113-30. doi: 10.1016/bs.apha.2015.03.004. Epub 2015 May 11. Adv Pharmacol. 2015. PMID: 26233905 Review.

4

Pre-treatment evaluation of 5-fluorouracil degradation rate: association of poor and ultra-rapid metabolism with severe toxicity in a colorectal cancer patients cohort.

Mazzuca F, Borro M, Botticelli A, Mazzotti E, Marchetti L, Gentile G, La Torre M, Lionetto L, Simmaco M, Marchetti P. Mazzuca F, et al. Among authors: simmaco m. Oncotarget. 2016 Apr 12;7(15):20612-20. doi: 10.18632/oncotarget.7991. Oncotarget. 2016. PMID: 26967565 Free PMC article.

5

CYP19A1 Genetic Polymorphisms rs4646 and Osteoporosis in Patients Treated with Aromatase Inhibitor-Based Adjuvant Therapy.

Mazzuca F, Botticelli A, Mazzotti E, La Torre M, Borro M, Marchetti L, Maddalena C, Gentile G, Simmaco M, Marchetti P. Mazzuca F, et al. Among authors: simmaco m. Eurasian J Med. 2016 Feb;48(1):10-4. doi: 10.5152/eurasianjmed.2015.008. Epub 2015 Jul 7. Eurasian J Med. 2016. PMID: 27026757 Free PMC article.

6

The TYMS-TSER polymorphism is associated with toxicity of low-dose capecitabine in patients with advanced gastrointestinal cancer.

Romiti A, Roberto M, D'Antonio C, Onesti CE, Barucca V, Milano A, Gentile G, Lionetto L, Medda E, Mazzuca F, Botticelli A, Falcone R, Simmaco M, Marchetti P. Romiti A, et al. Among authors: simmaco m. Anticancer Drugs. 2016 Nov;27(10):1044-9. doi: 10.1097/CAD.0000000000000429. Anticancer Drugs. 2016. PMID: 27557140

7

Degradation Rate of 5-Fluorouracil in Metastatic Colorectal Cancer: A New Predictive Outcome Biomarker?

Botticelli A, Borro M, Onesti CE, Strigari L, Gentile G, Cerbelli B, Romiti A, Occhipinti M, Sebastiani C, Lionetto L, Marchetti L, Simmaco M, Marchetti P, Mazzuca F. Botticelli A, et al. Among authors: simmaco m. PLoS One. 2016 Sep 22;11(9):e0163105. doi: 10.1371/journal.pone.0163105. eCollection 2016. PLoS One. 2016. PMID: 27656891 Free PMC article.

8

Pre-treatment assay of 5-fluorouracil degradation rate (5-FUDR) to improve prediction of 5-fluorouracil toxicity in gastro-esophageal cancer.

Borro M, Botticelli A, Mazzuca F, Onesti EC, Gentile G, Romiti A, Cerbelli B, Mazzotti E, Marchetti L, Lionetto L, Simmaco M, Marchetti P. Borro M, et al. Among authors: simmaco m. Oncotarget. 2017 Feb 21;8(8):14050-14057. doi: 10.18632/oncotarget.12571. Oncotarget. 2017. PMID: 27738344 Free PMC article.

9

5-Fluorouracil degradation rate could predict toxicity in stages II-III colorectal cancer patients undergoing adjuvant FOLFOX.

Onesti CE, Botticelli A, La Torre M, Borro M, Gentile G, Romiti A, Lionetto L, Petremolo A, Occhipinti M, Roberto M, Falcone R, Simmaco M, Marchetti P, Mazzuca F. Onesti CE, et al. Among authors: simmaco m. Anticancer Drugs. 2017 Mar;28(3):322-326. doi: 10.1097/CAD.0000000000000453. Anticancer Drugs. 2017. PMID: 27845948

10

Evaluation of 5-fluorouracil degradation rate and Pharmacogenetic profiling to predict toxicity following adjuvant Capecitabine.

Roberto M, Romiti A, Botticelli A, Mazzuca F, Lionetto L, Gentile G, Paris I, Falcone R, Bassanelli M, Di Pietro FR, Onesti CE, Anselmi E, Macrini S, Simmaco M, Marchetti P. Roberto M, et al. Among authors: simmaco m. Eur J Clin Pharmacol. 2017 Feb;73(2):157-164. doi: 10.1007/s00228-016-2160-8. Epub 2016 Nov 18. Eur J Clin Pharmacol. 2017. PMID: 27864592

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