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2-Hexylthio-β,γ-CH2-ATP is an effective and selective NTPDase2 inhibitor.
Gillerman I, Lecka J, Simhaev L, Munkonda MN, Fausther M, Martín-Satué M, Senderowitz H, Sévigny J, Fischer B. Gillerman I, et al. Among authors: simhaev l. J Med Chem. 2014 Jul 24;57(14):5919-34. doi: 10.1021/jm401933c. Epub 2014 Jul 14. J Med Chem. 2014. PMID: 24972256
An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.
Cui G, Hong J, Chung-Davidson YW, Infield D, Xu X, Li J, Simhaev L, Khazanov N, Stauffer B, Imhoff B, Cottrill K, Blalock JE, Li W, Senderowitz H, Sorscher E, McCarty NA, Gaggar A. Cui G, et al. Among authors: simhaev l. Dev Cell. 2019 Nov 18;51(4):421-430.e3. doi: 10.1016/j.devcel.2019.09.017. Epub 2019 Oct 31. Dev Cell. 2019. PMID: 31679858 Free PMC article.
The Q359K/T360K mutation causes cystic fibrosis in Georgian Jews.
Mei-Zahav M, Stafler P, Senderowitz H, Bentur L, Livnat G, Shteinberg M, Orenstein N, Bazak L, Prais D, Levine H, Gur M, Khazanov N, Simhaev L, Eliyahu H, Cohen M, Wilschanski M, Blau H, Mussaffi H. Mei-Zahav M, et al. Among authors: simhaev l. J Cyst Fibros. 2018 Sep;17(5):e41-e45. doi: 10.1016/j.jcf.2018.06.008. Epub 2018 Jul 20. J Cyst Fibros. 2018. PMID: 30033373 Free article.
Chemical Chaperones Modulate the Formation of Metabolite Assemblies.
Adsi H, Levkovich SA, Haimov E, Kreiser T, Meli M, Engel H, Simhaev L, Karidi-Heller S, Colombo G, Gazit E, Laor Bar-Yosef D. Adsi H, et al. Among authors: simhaev l. Int J Mol Sci. 2021 Aug 25;22(17):9172. doi: 10.3390/ijms22179172. Int J Mol Sci. 2021. PMID: 34502079 Free PMC article.
17 results