Simeoni F - Search Results

1

A stress-responsive enhancer induces dynamic drug resistance in acute myeloid leukemia.

Williams MS, Amaral FM, Simeoni F, Somervaille TC. Williams MS, et al. Among authors: simeoni f. J Clin Invest. 2020 Mar 2;130(3):1217-1232. doi: 10.1172/JCI130809. J Clin Invest. 2020. PMID: 31770110 Free PMC article.

2

Derepression of the Iroquois Homeodomain Transcription Factor Gene IRX3 Confers Differentiation Block in Acute Leukemia.

Somerville TDD, Simeoni F, Chadwick JA, Williams EL, Spencer GJ, Boros K, Wirth C, Tholouli E, Byers RJ, Somervaille TCP. Somerville TDD, et al. Among authors: simeoni f. Cell Rep. 2018 Jan 16;22(3):638-652. doi: 10.1016/j.celrep.2017.12.063. Cell Rep. 2018. PMID: 29346763 Free PMC article.

3

Revert the SIRT: Normalizing SIRT1 Activity in Myelodysplastic Stem Cells.

Simeoni F, Somervaille TCP. Simeoni F, et al. Cell Stem Cell. 2018 Sep 6;23(3):315-317. doi: 10.1016/j.stem.2018.08.003. Cell Stem Cell. 2018. PMID: 30193128 Free article.

4

Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis.

Yoshimi A, Lin KT, Wiseman DH, Rahman MA, Pastore A, Wang B, Lee SC, Micol JB, Zhang XJ, de Botton S, Penard-Lacronique V, Stein EM, Cho H, Miles RE, Inoue D, Albrecht TR, Somervaille TCP, Batta K, Amaral F, Simeoni F, Wilks DP, Cargo C, Intlekofer AM, Levine RL, Dvinge H, Bradley RK, Wagner EJ, Krainer AR, Abdel-Wahab O. Yoshimi A, et al. Among authors: simeoni f. Nature. 2019 Oct;574(7777):273-277. doi: 10.1038/s41586-019-1618-0. Epub 2019 Oct 2. Nature. 2019. PMID: 31578525 Free PMC article.

5

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.

Simeoni F, Romero-Camarero I, Camera F, Amaral FMR, Sinclair OJ, Papachristou EK, Spencer GJ, Lie-A-Ling M, Lacaud G, Wiseman DH, Carroll JS, Somervaille TCP. Simeoni F, et al. Cell Rep. 2021 Sep 21;36(12):109725. doi: 10.1016/j.celrep.2021.109725. Cell Rep. 2021. PMID: 34551306 Free PMC article.

6

Enhancer recruitment of a RUNX1, HDAC1 and TLE3 co-repressor complex by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.

Simeoni F, Somervaille TC. Simeoni F, et al. Mol Cell Oncol. 2021 Nov 19;8(6):2003161. doi: 10.1080/23723556.2021.2003161. eCollection 2021. Mol Cell Oncol. 2021. PMID: 35419467 Free PMC article.

7

HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block.

Maiques-Diaz A, Nicosia L, Basma NJ, Romero-Camarero I, Camera F, Spencer GJ, Amaral FMR, Simeoni F, Wingelhofer B, Williamson AJK, Pierce A, Whetton AD, Somervaille TCP. Maiques-Diaz A, et al. Among authors: simeoni f. Oncogene. 2022 Oct;41(44):4841-4854. doi: 10.1038/s41388-022-02471-y. Epub 2022 Sep 28. Oncogene. 2022. PMID: 36171271 Free PMC article.

8

Differentiation block in acute myeloid leukemia regulated by intronic sequences of FTO.

Camera F, Romero-Camarero I, Revell BH, Amaral FMR, Sinclair OJ, Simeoni F, Wiseman DH, Stojic L, Somervaille TCP. Camera F, et al. Among authors: simeoni f. iScience. 2023 Jul 11;26(8):107319. doi: 10.1016/j.isci.2023.107319. eCollection 2023 Aug 18. iScience. 2023. PMID: 37539037 Free PMC article.

9

Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia.

Mori M, Tottone L, Quaglio D, Zhdanovskaya N, Ingallina C, Fusto M, Ghirga F, Peruzzi G, Crestoni ME, Simeoni F, Giulimondi F, Talora C, Botta B, Screpanti I, Palermo R. Mori M, et al. Among authors: simeoni f. Sci Rep. 2017 May 19;7(1):2213. doi: 10.1038/s41598-017-02316-9. Sci Rep. 2017. PMID: 28526832 Free PMC article.

10

Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL.

Tottone L, Zhdanovskaya N, Carmona Pestaña Á, Zampieri M, Simeoni F, Lazzari S, Ruocco V, Pelullo M, Caiafa P, Felli MP, Checquolo S, Bellavia D, Talora C, Screpanti I, Palermo R. Tottone L, et al. Among authors: simeoni f. Front Oncol. 2019 Apr 3;9:198. doi: 10.3389/fonc.2019.00198. eCollection 2019. Front Oncol. 2019. PMID: 31001470 Free PMC article.

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