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Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.
Joas S, Parrish EH, Gnanadurai CW, Lump E, Stürzel CM, Parrish NF, Learn GH, Sauermann U, Neumann B, Rensing KM, Fuchs D, Billingsley JM, Bosinger SE, Silvestri G, Apetrei C, Huot N, Garcia-Tellez T, Müller-Trutwin M, Hotter D, Sauter D, Stahl-Hennig C, Hahn BH, Kirchhoff F. Joas S, et al. Among authors: silvestri g. Nat Commun. 2018 Apr 10;9(1):1371. doi: 10.1038/s41467-018-03762-3. Nat Commun. 2018. PMID: 29636452 Free PMC article.
Apoptosis in SIV infection.
Hurtrel B, Petit F, Arnoult D, Müller-Trutwin M, Silvestri G, Estaquier J. Hurtrel B, et al. Among authors: silvestri g. Cell Death Differ. 2005 Aug;12 Suppl 1:979-90. doi: 10.1038/sj.cdd.4401600. Cell Death Differ. 2005. PMID: 15818408 Review.
The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus.
Dunham R, Pagliardini P, Gordon S, Sumpter B, Engram J, Moanna A, Paiardini M, Mandl JN, Lawson B, Garg S, McClure HM, Xu YX, Ibegbu C, Easley K, Katz N, Pandrea I, Apetrei C, Sodora DL, Staprans SI, Feinberg MB, Silvestri G. Dunham R, et al. Among authors: silvestri g. Blood. 2006 Jul 1;108(1):209-17. doi: 10.1182/blood-2005-12-4897. Epub 2006 Mar 7. Blood. 2006. PMID: 16522814 Free PMC article.
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
Schindler M, Münch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Müller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F. Schindler M, et al. Among authors: silvestri g. Cell. 2006 Jun 16;125(6):1055-67. doi: 10.1016/j.cell.2006.04.033. Cell. 2006. PMID: 16777597 Free article.
Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts.
Pandrea I, Apetrei C, Gordon S, Barbercheck J, Dufour J, Bohm R, Sumpter B, Roques P, Marx PA, Hirsch VM, Kaur A, Lackner AA, Veazey RS, Silvestri G. Pandrea I, et al. Among authors: silvestri g. Blood. 2007 Feb 1;109(3):1069-76. doi: 10.1182/blood-2006-05-024364. Epub 2006 Sep 26. Blood. 2007. PMID: 17003371 Free PMC article.
In vitro characterization of primary SIVsmm isolates belonging to different lineages. In vitro growth on rhesus macaque cells is not predictive for in vivo replication in rhesus macaques.
Gautam R, Carter AC, Katz N, Butler IF, Barnes M, Hasegawa A, Ratterree M, Silvestri G, Marx PA, Hirsch VM, Pandrea I, Apetrei C. Gautam R, et al. Among authors: silvestri g. Virology. 2007 Jun 5;362(2):257-70. doi: 10.1016/j.virol.2006.12.037. Epub 2007 Feb 15. Virology. 2007. PMID: 17303205 Free PMC article.
1,047 results