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Cyclophilin A is a ligand for RAGE in thrombo-inflammation.
Seizer P, von Ungern-Sternberg SNI, Haug V, Dicenta V, Rosa A, Butt E, Nöthel M, Rohlfing AK, Sigle M, Nawroth PP, Nussbaum C, Sperandio M, Kusch C, Meub M, Sauer M, Münzer P, Bieber K, Stanger A, Mack AF, Huber R, Brand K, Lehners M, Feil R, Poso A, Krutzke K, Schäffer TE, Nieswandt B, Borst O, May AE, Zernecke A, Gawaz M, Heinzmann D. Seizer P, et al. Among authors: sigle m. Cardiovasc Res. 2024 Mar 30;120(4):385-402. doi: 10.1093/cvr/cvad189. Cardiovasc Res. 2024. PMID: 38175781
cGMP modulates hemin-mediated platelet death.
Rohlfing AK, Kremser M, Schaale D, Dicenta-Baunach V, Laspa Z, Fu X, Zizmare L, Sigle M, Harm T, Münzer P, Pelzer A, Borst O, Trautwein C, Feil R, Müller K, Castor T, Lämmerhofer M, Gawaz MP. Rohlfing AK, et al. Among authors: sigle m. Thromb Res. 2024 Feb;234:63-74. doi: 10.1016/j.thromres.2023.12.008. Epub 2023 Dec 21. Thromb Res. 2024. PMID: 38171216
Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation.
de Jonckheere B, Kollotzek F, Münzer P, Göb V, Fischer M, Mott K, Coman C, Troppmair NN, Manke MC, Zdanyte M, Harm T, Sigle M, Kopczynski D, Bileck A, Gerner C, Hoffmann N, Heinzmann D, Assinger A, Gawaz M, Stegner D, Schulze H, Borst O, Ahrends R. de Jonckheere B, et al. Among authors: sigle m. Nat Cardiovasc Res. 2023 Sep;2:835-852. doi: 10.1038/s44161-023-00325-8. Epub 2023 Aug 31. Nat Cardiovasc Res. 2023. PMID: 38075556 Free PMC article.
ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury.
Rohlfing AK, Kolb K, Sigle M, Ziegler M, Bild A, Münzer P, Sudmann J, Dicenta V, Harm T, Manke MC, Geue S, Kremser M, Chatterjee M, Liang C, von Eysmondt H, Dandekar T, Heinzmann D, Günter M, von Ungern-Sternberg S, Büttcher M, Castor T, Mencl S, Langhauser F, Sies K, Ashour D, Beker MC, Lämmerhofer M, Autenrieth SE, Schäffer TE, Laufer S, Szklanna P, Maguire P, Heikenwalder M, Müller KAL, Hermann DM, Kilic E, Stumm R, Ramos G, Kleinschnitz C, Borst O, Langer HF, Rath D, Gawaz M. Rohlfing AK, et al. Among authors: sigle m. Nat Commun. 2022 Apr 5;13(1):1823. doi: 10.1038/s41467-022-29341-1. Nat Commun. 2022. PMID: 35383158 Free PMC article.
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