Siekierka J - Search Results

1

Tranilast: a pharmaceutical candidate for reduction of adhesions using a novel approach.

Petrilli J, Wadsworth S, Cooper K, Rodgers KE, Siekierka J, diZerega GS. Petrilli J, et al. Among authors: siekierka j. Semin Reprod Med. 2008 Jul;26(4):341-8. doi: 10.1055/s-0028-1082392. Semin Reprod Med. 2008. PMID: 18756411 Review.

2

p38 alpha mitogen-activated protein kinase is activated by CD28-mediated signaling and is required for IL-4 production by human CD4+CD45RO+ T cells and Th2 effector cells.

Schafer PH, Wadsworth SA, Wang L, Siekierka JJ. Schafer PH, et al. Among authors: siekierka jj. J Immunol. 1999 Jun 15;162(12):7110-9. J Immunol. 1999. PMID: 10358155

3

Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.

Tao L, Wadsworth S, Mercer J, Mueller C, Lynn K, Siekierka J, August A. Tao L, et al. Among authors: siekierka j. Biochem J. 2002 Apr 1;363(Pt 1):175-82. doi: 10.1042/0264-6021:3630175. Biochem J. 2002. PMID: 11903060 Free PMC article.

4

T cell activation signals up-regulate p38 mitogen-activated protein kinase activity and induce TNF-alpha production in a manner distinct from LPS activation of monocytes.

Schafer PH, Wang L, Wadsworth SA, Davis JE, Siekierka JJ. Schafer PH, et al. Among authors: siekierka jj. J Immunol. 1999 Jan 15;162(2):659-68. J Immunol. 1999. PMID: 9916683

5

Imidazopyrimidines, potent inhibitors of p38 MAP kinase.

Rupert KC, Henry JR, Dodd JH, Wadsworth SA, Cavender DE, Olini GC, Fahmy B, Siekierka JJ. Rupert KC, et al. Among authors: siekierka jj. Bioorg Med Chem Lett. 2003 Feb 10;13(3):347-50. doi: 10.1016/s0960-894x(02)01020-x. Bioorg Med Chem Lett. 2003. PMID: 12565927

6

Inhibitors of unactivated p38 MAP kinase.

Bullington J, Argentieri D, Averill K, Carter D, Cavender D, Fahmy B, Fan X, Hall D, Heintzelman G, Jackson P, Leung WP, Li X, Ling P, Olini G, Razler T, Reuman M, Rupert K, Russell R, Siekierka J, Wadsworth S, Wolff R, Xiang B, Zhang YM. Bullington J, et al. Among authors: siekierka j. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6102-6. doi: 10.1016/j.bmcl.2006.08.101. Epub 2006 Sep 12. Bioorg Med Chem Lett. 2006. PMID: 16971122

7

Potent inhibitors of the MAP kinase p38.

Henry JR, Rupert KC, Dodd JH, Turchi IJ, Wadsworth SA, Cavender DE, Schafer PH, Siekierka JJ. Henry JR, et al. Among authors: siekierka jj. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3335-40. doi: 10.1016/s0960-894x(98)00589-7. Bioorg Med Chem Lett. 1998. PMID: 9873730

8

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production.

Kanakaraj P, Schafer PH, Cavender DE, Wu Y, Ngo K, Grealish PF, Wadsworth SA, Peterson PA, Siekierka JJ, Harris CA, Fung-Leung WP. Kanakaraj P, et al. Among authors: siekierka jj. J Exp Med. 1998 Jun 15;187(12):2073-9. doi: 10.1084/jem.187.12.2073. J Exp Med. 1998. PMID: 9625767 Free PMC article.

9

6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2, 3-b]pyridine (RWJ 68354): a potent and selective p38 kinase inhibitor.

Henry JR, Rupert KC, Dodd JH, Turchi IJ, Wadsworth SA, Cavender DE, Fahmy B, Olini GC, Davis JE, Pellegrino-Gensey JL, Schafer PH, Siekierka JJ. Henry JR, et al. Among authors: siekierka jj. J Med Chem. 1998 Oct 22;41(22):4196-8. doi: 10.1021/jm980497b. J Med Chem. 1998. PMID: 9784093 No abstract available.

10

A multiplexed proteomics approach to differentiate neurite outgrowth patterns.

Liu T, D'mello V, Deng L, Hu J, Ricardo M, Pan S, Lu X, Wadsworth S, Siekierka J, Birge R, Li H. Liu T, et al. Among authors: siekierka j. J Neurosci Methods. 2006 Nov 15;158(1):22-9. doi: 10.1016/j.jneumeth.2006.05.010. Epub 2006 Jun 23. J Neurosci Methods. 2006. PMID: 16797718 Free PMC article.

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