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Anetumab ravtansine versus vinorelbine in patients with relapsed, mesothelin-positive malignant pleural mesothelioma (ARCS-M): a randomised, open-label phase 2 trial.
Kindler HL, Novello S, Bearz A, Ceresoli GL, Aerts JGJV, Spicer J, Taylor P, Nackaerts K, Greystoke A, Jennens R, Calabrò L, Burgers JA, Santoro A, Cedrés S, Serwatowski P, Ponce S, Van Meerbeeck JP, Nowak AK, Blumenschein G Jr, Siegel JM, Kasten L, Köchert K, Walter AO, Childs BH, Elbi C, Hassan R, Fennell DA. Kindler HL, et al. Among authors: siegel jm. Lancet Oncol. 2022 Apr;23(4):540-552. doi: 10.1016/S1470-2045(22)00061-4. Lancet Oncol. 2022. PMID: 35358455 Free PMC article. Clinical Trial.
Safety and activity of anti-mesothelin antibody-drug conjugate anetumab ravtansine in combination with pegylated-liposomal doxorubicin in platinum-resistant ovarian cancer: multicenter, phase Ib dose escalation and expansion study.
Santin AD, Vergote I, González-Martín A, Moore K, Oaknin A, Romero I, Diab S, Copeland LJ, Monk BJ, Coleman RL, Herzog TJ, Siegel J, Kasten L, Schlicker A, Schulz A, Köchert K, Walter AO, Childs BH, Elbi C, Bulat I. Santin AD, et al. Int J Gynecol Cancer. 2023 Apr 3;33(4):562-570. doi: 10.1136/ijgc-2022-003927. Int J Gynecol Cancer. 2023. PMID: 36564099 Free PMC article. Clinical Trial.
Sleep: Giving it up to get it on.
Lyamin OI, Siegel JM. Lyamin OI, et al. Among authors: siegel jm. Curr Biol. 2024 Mar 11;34(5):R213-R216. doi: 10.1016/j.cub.2024.01.061. Curr Biol. 2024. PMID: 38471454
Radium-223 in women with hormone receptor-positive bone-metastatic breast cancer receiving endocrine therapy: pooled analysis of two international, phase 2, randomized, double-blind, placebo-controlled trials.
Rugo HS, Van Poznak CH, Neven P, Danielewicz I, Lee SC, Campone M, Chik JYK, Vega Alonso E, Naume B, Brain E, Siegel JM, Li R, Uema D, Wagner VJ, Coleman RE. Rugo HS, et al. Among authors: siegel jm. Breast Cancer Res Treat. 2024 Apr;204(2):249-259. doi: 10.1007/s10549-023-07147-z. Epub 2023 Dec 20. Breast Cancer Res Treat. 2024. PMID: 38123789 Free PMC article. Clinical Trial.
Opiate anticipation, opiate induced anatomical changes in hypocretin (Hcrt, orexin) neurons and opiate induced microglial activation are blocked by the dual Hcrt receptor antagonist suvorexant, while opiate analgesia is maintained.
McGregor R, Wu MF, Thannickal TC, Siegel JM. McGregor R, et al. Among authors: siegel jm. bioRxiv [Preprint]. 2024 Feb 17:2023.09.22.559044. doi: 10.1101/2023.09.22.559044. bioRxiv. 2024. PMID: 37790444 Free PMC article. Preprint.
REM sleep function: Mythology vs. reality.
Siegel JM. Siegel JM. Rev Neurol (Paris). 2023 Oct;179(7):643-648. doi: 10.1016/j.neurol.2023.08.002. Epub 2023 Aug 23. Rev Neurol (Paris). 2023. PMID: 37625974 Free PMC article. Review.
323 results