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Engineered SH2 Domains for Targeted Phosphoproteomics.
Martyn GD, Veggiani G, Kusebauch U, Morrone SR, Yates BP, Singer AU, Tong J, Manczyk N, Gish G, Sun Z, Kurinov I, Sicheri F, Moran MF, Moritz RL, Sidhu SS. Martyn GD, et al. Among authors: sidhu ss. ACS Chem Biol. 2022 Jun 17;17(6):1472-1484. doi: 10.1021/acschembio.2c00051. Epub 2022 May 25. ACS Chem Biol. 2022. PMID: 35613471 Free PMC article.
The multiple-specificity landscape of modular peptide recognition domains.
Gfeller D, Butty F, Wierzbicka M, Verschueren E, Vanhee P, Huang H, Ernst A, Dar N, Stagljar I, Serrano L, Sidhu SS, Bader GD, Kim PM. Gfeller D, et al. Among authors: sidhu ss. Mol Syst Biol. 2011 Apr 26;7:484. doi: 10.1038/msb.2011.18. Mol Syst Biol. 2011. PMID: 21525870 Free PMC article.
A strategy for modulation of enzymes in the ubiquitin system.
Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, Landry MC, Yeh C, Zeqiraj E, Karamboulas K, Allali-Hassani A, Vedadi M, Tyers M, Moffat J, Sicheri F, Pelletier L, Durocher D, Raught B, Rotin D, Yang J, Moran MF, Dhe-Paganon S, Sidhu SS. Ernst A, et al. Among authors: sidhu ss. Science. 2013 Feb 1;339(6119):590-5. doi: 10.1126/science.1230161. Epub 2013 Jan 3. Science. 2013. PMID: 23287719 Free PMC article.
Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.
Findlay GM, Smith MJ, Lanner F, Hsiung MS, Gish GD, Petsalaki E, Cockburn K, Kaneko T, Huang H, Bagshaw RD, Ketela T, Tucholska M, Taylor L, Bowtell DD, Moffat J, Ikura M, Li SS, Sidhu SS, Rossant J, Pawson T. Findlay GM, et al. Among authors: sidhu ss. Cell. 2013 Feb 28;152(5):1008-20. doi: 10.1016/j.cell.2013.01.056. Cell. 2013. PMID: 23452850 Free article.
SH3 interactome conserves general function over specific form.
Xin X, Gfeller D, Cheng J, Tonikian R, Sun L, Guo A, Lopez L, Pavlenco A, Akintobi A, Zhang Y, Rual JF, Currell B, Seshagiri S, Hao T, Yang X, Shen YA, Salehi-Ashtiani K, Li J, Cheng AT, Bouamalay D, Lugari A, Hill DE, Grimes ML, Drubin DG, Grant BD, Vidal M, Boone C, Sidhu SS, Bader GD. Xin X, et al. Among authors: sidhu ss. Mol Syst Biol. 2013;9:652. doi: 10.1038/msb.2013.9. Mol Syst Biol. 2013. PMID: 23549480 Free PMC article.
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.
Huang H, Ceccarelli DF, Orlicky S, St-Cyr DJ, Ziemba A, Garg P, Plamondon S, Auer M, Sidhu S, Marinier A, Kleiger G, Tyers M, Sicheri F. Huang H, et al. Nat Chem Biol. 2014 Feb;10(2):156-163. doi: 10.1038/nchembio.1412. Epub 2013 Dec 15. Nat Chem Biol. 2014. PMID: 24316736 Free PMC article.
A structural portrait of the PDZ domain family.
Ernst A, Appleton BA, Ivarsson Y, Zhang Y, Gfeller D, Wiesmann C, Sidhu SS. Ernst A, et al. Among authors: sidhu ss. J Mol Biol. 2014 Oct 23;426(21):3509-19. doi: 10.1016/j.jmb.2014.08.012. Epub 2014 Aug 23. J Mol Biol. 2014. PMID: 25158098
460 results