Sidhom PA - Search Results

1

Terminators or Guardians? Design, Synthesis, and Cytotoxicity Profiling of Chalcone-Sulfonamide Hybrids.

Aboukhatwa SM, Sidhom PA, Angeli A, Supuran CT, Tawfik HO. Aboukhatwa SM, et al. Among authors: sidhom pa. ACS Omega. 2023 Feb 17;8(8):7666-7683. doi: 10.1021/acsomega.2c07285. eCollection 2023 Feb 28. ACS Omega. 2023. PMID: 36872984 Free PMC article.

2

Preferability of Molnupiravir, an Anti-COVID-19 Drug, toward Purine Nucleosides: A Quantum Mechanical Study.

Ibrahim MAA, Shehata MNI, Moussa NAM, Hemia RRA, Abd Elhafez HSM, Abd El-Rahman MK, Sayed SRM, Sidhom PA, Dabbish E, Shoeib T. Ibrahim MAA, et al. Among authors: sidhom pa. ACS Omega. 2023 Jul 18;8(30):27553-27565. doi: 10.1021/acsomega.3c03215. eCollection 2023 Aug 1. ACS Omega. 2023. PMID: 37546583 Free PMC article.

3

Revisiting ageless antiques; synthesis, biological evaluation, docking simulation and mechanistic insights of 1,4-Dihydropyridines as anticancer agents.

Sidhom PA, El-Bastawissy E, Salama AA, El-Moselhy TF. Sidhom PA, et al. Bioorg Chem. 2021 Sep;114:105054. doi: 10.1016/j.bioorg.2021.105054. Epub 2021 Jun 4. Bioorg Chem. 2021. PMID: 34146919

4

The mystery of titan hunter: Rationalized striking of the MAPK pathway via Newly synthesized 6-Indolylpyridone-3-Carbonitrile derivatives.

Saleh MM, El-Moselhy T, El-Bastawissy E, Ibrahim MAA, Sayed SRM, Hegazy MF, Efferth T, Jaragh-Alhadad LA, Sidhom PA. Saleh MM, et al. Among authors: sidhom pa. Eur J Med Chem. 2023 Nov 5;259:115675. doi: 10.1016/j.ejmech.2023.115675. Epub 2023 Jul 23. Eur J Med Chem. 2023. PMID: 37506545

5

Synthesis and Evaluation of Novel S-alkyl Phthalimide- and S-benzyl-oxadiazole-quinoline Hybrids as Inhibitors of Monoamine Oxidase and Acetylcholinesterase.

Khan BA, Hamdani SS, Jalil S, Ejaz SA, Iqbal J, Shawky AM, Alqahtani AM, Gabr GA, Ibrahim MAA, Sidhom PA. Khan BA, et al. Among authors: sidhom pa. Pharmaceuticals (Basel). 2022 Dec 22;16(1):11. doi: 10.3390/ph16010011. Pharmaceuticals (Basel). 2022. PMID: 36678507 Free PMC article.

6

Synthesis, Docking Simulation, Biological Evaluations and 3D-QSAR Study of 1,4-Dihydropyridines as Calcium Channel Blockers.

El-Moselhy TF, Sidhom PA, Esmat EA, El-Mahdy NA. El-Moselhy TF, et al. Among authors: sidhom pa. Chem Pharm Bull (Tokyo). 2017;65(10):893-903. doi: 10.1248/cpb.c17-00186. Chem Pharm Bull (Tokyo). 2017. PMID: 28966273 Free article.

7

Mechanistic Insight of Synthesized 1,4-Dihydropyridines as an Antidiabetic Sword against Reactive Oxygen Species.

Sidhom PA, El-Bastawissy E, Ibrahim MAA, Shawky AM, Salama A, El-Moselhy T. Sidhom PA, et al. J Med Chem. 2023 Jan 12;66(1):991-1010. doi: 10.1021/acs.jmedchem.2c01818. Epub 2022 Dec 30. J Med Chem. 2023. PMID: 36584305

8

Synthesis, X-ray diffraction analysis, quantum chemical studies and α-amylase inhibition of probenecid derived S-alkylphthalimide-oxadiazole-benzenesulfonamide hybrids.

Khan BA, Hamdani SS, Ahmed MN, Hameed S, Ashfaq M, Shawky AM, Ibrahim MAA, Sidhom PA. Khan BA, et al. Among authors: sidhom pa. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1464-1478. doi: 10.1080/14756366.2022.2078969. J Enzyme Inhib Med Chem. 2022. PMID: 35616297 Free PMC article.

9

Inherent efficacies of pyrazole-based derivatives for cancer therapy: the interface between experiment and in silico.

Dube ZF, Soremekun OS, Ntombela T, Alahmdi MI, Abo-Dya NE, Sidhom PA, Shawky AM, Shibl MF, Ibrahim MA, Soliman ME. Dube ZF, et al. Among authors: sidhom pa. Future Med Chem. 2023 Sep;15(18):1719-1738. doi: 10.4155/fmc-2023-0142. Epub 2023 Sep 29. Future Med Chem. 2023. PMID: 37772542 Review.

10

In-Silico Mining of the Toxins Database (T3DB) towards Hunting Prospective Candidates as ABCB1 Inhibitors: Integrated Molecular Docking and Lipid Bilayer-Enhanced Molecular Dynamics Study.

Ibrahim MAA, Abdeljawaad KAA, Abdelrahman AHM, Sidhom PA, Tawfeek AM, Mekhemer GAH, Abd El-Rahman MK, Dabbish E, Shoeib T. Ibrahim MAA, et al. Among authors: sidhom pa. Pharmaceuticals (Basel). 2023 Jul 18;16(7):1019. doi: 10.3390/ph16071019. Pharmaceuticals (Basel). 2023. PMID: 37513931 Free PMC article.

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