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Complete loss of H3K9 methylation dissolves mouse heterochromatin organization.
Montavon T, Shukeir N, Erikson G, Engist B, Onishi-Seebacher M, Ryan D, Musa Y, Mittler G, Meyer AG, Genoud C, Jenuwein T. Montavon T, et al. Among authors: shukeir n. Nat Commun. 2021 Jul 16;12(1):4359. doi: 10.1038/s41467-021-24532-8. Nat Commun. 2021. PMID: 34272378 Free PMC article.
m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin.
Duda KJ, Ching RW, Jerabek L, Shukeir N, Erikson G, Engist B, Onishi-Seebacher M, Perrera V, Richter F, Mittler G, Fritz K, Helm M, Knuckles P, Bühler M, Jenuwein T. Duda KJ, et al. Among authors: shukeir n. Nucleic Acids Res. 2021 Jun 4;49(10):5568-5587. doi: 10.1093/nar/gkab364. Nucleic Acids Res. 2021. PMID: 33999208 Free PMC article.
H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction.
Healton SE, Pinto HD, Mishra LN, Hamilton GA, Wheat JC, Swist-Rosowska K, Shukeir N, Dou Y, Steidl U, Jenuwein T, Gamble MJ, Skoultchi AI. Healton SE, et al. Among authors: shukeir n. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14251-14258. doi: 10.1073/pnas.1920725117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513732 Free PMC article.
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation.
Velazquez Camacho O, Galan C, Swist-Rosowska K, Ching R, Gamalinda M, Karabiber F, De La Rosa-Velazquez I, Engist B, Koschorz B, Shukeir N, Onishi-Seebacher M, van de Nobelen S, Jenuwein T. Velazquez Camacho O, et al. Among authors: shukeir n. Elife. 2017 Aug 1;6:e25293. doi: 10.7554/eLife.25293. Elife. 2017. PMID: 28760199 Free PMC article.
14 results